Central memory and effector memory T cell subsets: function, generation, and maintenance

F Sallusto, J Geginat, A Lanzavecchia - Annu. Rev. Immunol., 2004 - annualreviews.org
The memory T cell pool functions as a dynamic repository of antigen-experienced T
lymphocytes that accumulate over the lifetime of the individual. Recent studies indicate that …

Understanding the generation and function of memory T cell subsets

A Lanzavecchia, F Sallusto - Current opinion in immunology, 2005 - Elsevier
Memory T cells can be broadly divided into central memory and effector memory subsets,
which are endowed with different capacities to home to lymphoid or non-lymphoid tissues, to …

Development, trafficking, and function of memory T‐cell subsets

L Lefrançois - Immunological reviews, 2006 - Wiley Online Library
The precise mechanisms that govern memory T‐cell lineage commitment during an immune
response continue to be the subject of intense scrutiny. The existence of memory T‐cell …

Cytokine-driven Proliferation and Differentiation of Human Naive, Central Memory, and Effector Memory CD4+ T Cells

J Geginat, F Sallusto, A Lanzavecchia - The Journal of experimental …, 2001 - rupress.org
Memory T lymphocytes proliferate in vivo in the absence of antigen maintaining a pool of
central memory T cells (TCM) and effector memory T cells (TEM) with distinct effector …

[HTML][HTML] Initial T cell frequency dictates memory CD8+ T cell lineage commitment

AL Marzo, KD Klonowski, AL Bon, P Borrow… - Nature …, 2005 - nature.com
Memory T cells can be divided into central memory T cell (TCM cell) and effector memory T
cell (TEM cell) subsets based on homing characteristics and effector functions. Whether TEM …

Generation of effector CD8+ T cells and their conversion to memory T cells

W Cui, SM Kaech - Immunological reviews, 2010 - Wiley Online Library
Immunological memory is a cardinal feature of adaptive immunity. We are now beginning to
elucidate the mechanisms that govern the formation of memory T cells and their ability to …

[HTML][HTML] Bone marrow T cells and the integrated functions of recirculating and tissue-resident memory T cells

F Di Rosa, T Gebhardt - Frontiers in immunology, 2016 - frontiersin.org
Changes in T cell trafficking accompany the naive to memory T cell antigen-driven
differentiation, which remains an incompletely defined developmental step. Upon priming …

Cytokine-driven proliferation and differentiation of human naive, central memory and effector memory CD4+ T cells

J Geginat, F Sallusto, A Lanzavecchia - Pathologie Biologie, 2003 - Elsevier
Memory T lymphocytes divide in vivo in the absence of antigen maintaining a pool of central
memory (TCM) and effector memory cells (TEM) with distinct effector function and homing …

Human memory T cells: generation, compartmentalization and homeostasis

DL Farber, NA Yudanin, NP Restifo - Nature Reviews Immunology, 2014 - nature.com
Memory T cells constitute the most abundant lymphocyte population in the body for the
majority of a person's lifetime; however, our understanding of memory T cell generation …

Memory T cell subsets, migration patterns, and tissue residence

SN Mueller, T Gebhardt, FR Carbone… - Annual review of …, 2013 - annualreviews.org
Tissues such as the skin and mucosae are frequently exposed to microbial pathogens.
Infectious agents must be quickly and efficiently controlled by our immune system, but the …