Background—It has been suggested that infection with Chlamydia pneumoniae (CPn) can
trigger inflammatory mechanisms that may in turn impair vascular endothelial function. The …

There is widespread consensus that atherosclerosis is an inflammatory disease. Between
possible pathogenetic mechanisms, infective hypothesis has received increasing attention …

Objectives. We sought to examine coronary arteries for the presence of viable bacteria of the
fastidious species Chlamydia pneumoniae. Background. The respiratory pathogen C …

Aims: Since infection of endothelial or smooth muscle cells with Chlamydia pneumoniae
increased expression of tissue factor and plasminogen activator inhibitor I (PAI-1), C …

Aim: To clarify whether there is any association between the extent of Chlamydia
pneumoniae (C. pneumoniae) infection and plaque instability or post–directional coronary …

Objectives Stent implantation produces a systemic increase of inflammatory markers that
correlates with Chlamydophila pneumoniae infection in atherosclerotic plaque. We …

Objective: Drug-eluting stents containing the immunosuppressant rapamycin markedly
inhibit in stent restenosis (ISR). However, the molecular mechanisms that underlie its effect …

There can no longer be any doubt that viable Chlamydia pneumoniae organisms are
present in a therOSclerOfic lesions. Indeed, the endovascular presence of C. pneumoniae in …

Aberrant vascular smooth muscle cell (VSMC) growth and migration are associated with
many vascular occlusive diseases, including atherosclerosis, transplant vasculopathy, and …

There is increasing data implicating Chlamydia pneumoniae in the pathogenesis of
atherosclerosis, and antibiotics may theoretically be useful to prevent secondary vascular …