[引用][C] Digoxin drug interactions Comparative effects of verapamil and isradipine on steady-state digoxin kinetics

BF Johnson, J Wilson, R Marwaha, K Hoch, J Johnson

Modification of the inotropic effect of digoxin by diazepam in rat left atria

JR Castillo-Ferrando, E Perez-Ojeda… - Journal of pharmacy …, 1985 - academic.oup.com
There is a pharmacokinetic interaction between digoxin and diazepam that increases the
elimination half-life of digoxin. It may be due to a reduction of digoxin tissue concentrations …

Serum digoxin levels using an 125I-labelled antigen: Validation of method and observations on cardiac patients.

K Taubert, W Shapiro - American Heart Journal, 1975 - europepmc.org
1. Determinations of serum digoxin levels utilizing commercially available kits with an 125I-
labelled antigen were precise and not materially different from results obtained with a 3H …

3H-digoxin distribution in the nervous system in ventricular tachycardia

G Frazer, P Binnion - Journal of Cardiovascular Pharmacology, 1981 - journals.lww.com
The distribution of 3 H-digoxin has been measured in a large number of tissues from the
central, autonomic, and peripheral nervous system after the induction of ventricular …

The effects of central beta-receptor antagonism on digoxin cardiotoxicity.

LM Plunkett, RL Tackett - Research communications in chemical …, 1985 - europepmc.org
Pentobarbital-anesthetized dogs were pretreated centrally with either metoprolol, a selective
beta1 antagonist, or ICI 118,551, a selective beta2 antagonist, prior to a continuous digoxin …

Digoxin-quinidine interaction: pharmacokinetic evaluation

WD Hager, P Fenster, M Mayersohn… - … England Journal of …, 1979 - Mass Medical Soc
Several recent reports have shown that plasma concentrations of digoxin increase when
quinidine is administered along with digoxin; the present study was designed to explore the …

Lack of interaction between digoxin and quinidine in cultured heart cells.

JD Horowitz, WH Barry, TW Smith - Journal of Pharmacology and …, 1982 - ASPET
Previous investigations have raised the possibility that the digoxin-quinidine interaction is
associated with a reduction in the positive inotropic effect of digoxin due to displacement of …

Effects of nifedipine and diltiazem on plasma levels and renal excretion of beta‐acetyldigoxin

J Kuhlmann - Clinical Pharmacology & Therapeutics, 1985 - Wiley Online Library
To determine whether nifedipine or diltiazem affect digoxin kinetics, glycoside plasma
concentrations and renal excretion were measured before and during dosing in 23 patients …

Radioimmunoassay of serum digoxin in relation to digoxin intoxication.

RB Singh, AN Rai, DP Dube, DK Srivastav, PN Somani… - Heart, 1975 - heart.bmj.com
Serum digoxin estimations were done in 98 patients receiving digoxin for heart failure of
varied aetiology. Digoxin toxicity or the lack of it was determined on the basin of established …

Digoxin and digoxin derivative induced arrhythmias: in vitro binding and in vivo abolition of arrhythmias by digoxin immune Fab (DIGIBAND)

D Cambridge, CR Morgan, G Allen - Cardiovascular research, 1992 - academic.oup.com
Objective: The aim was to compare the binding characteristics of a highly purified digoxin
specific antigen binding fragment (digoxin immune Fab: digibind) with digoxin and with two …