The usefulness of thyroid antibodies in the diagnostic approach to autoimmune thyroid disease

H Vargas-Uricoechea, JP Nogueira… - Antibodies, 2023 - mdpi.com
Autoimmune thyroid disease (AITD) refers to a spectrum of various diseases, with two
extremes of clinical presentation, hypothyroidism (Hashimoto's thyroiditis (HT) and …

Thyroid autoimmunity: role of anti-thyroid antibodies in thyroid and extra-thyroidal diseases

E Fröhlich, R Wahl - Frontiers in immunology, 2017 - frontiersin.org
Autoimmune diseases have a high prevalence in the population, and autoimmune thyroid
disease (AITD) is one of the most common representatives. Thyroid autoantibodies are not …

Thyroid autoantibodies

SN Dwivedi, T Kalaria, H Buch - Journal of Clinical Pathology, 2023 - jcp.bmj.com
Thyroid-stimulating hormone (TSH) receptor antibody (TSH-R-Ab or TRAb) testing plays a
pivotal role in arriving at the aetiological diagnosis in patients with thyrotoxicosis. A positive …

Autoantibody profiling of patients with autoimmune thyroid disease using a new multiplexed immunoassay method

R Tozzoli, D Villalta, G Kodermaz… - Clinical Chemistry and …, 2006 - degruyter.com
Background: It has been proposed that only anti-thyroid-peroxidase (TPOAb) and not anti-
thyroglobulin (TgAb) antibodies should be assayed in the diagnosis of autoimmune thyroid …

Autoimmune thyroid disorders—An update

M Swain, T Swain, BK Mohanty - Indian Journal of Clinical Biochemistry, 2005 - Springer
Background: Autoimmune thyroid disease (AITD), a common organ specific autoimmune
disorder is seen mostly in women between 30–50 yrs of age. Thyroid autoimmunity can …

Immunopurification and characterization of thyroid autoantibodies with dual specificity for thyroglobulin and thyroperoxidase

J Ruf, M Ferrand, JÉEM Durand-gorde, P Carayon - Autoimmunity, 1992 - Taylor & Francis
The presence of autoantibodies (aAbs) to thyroglobulin (TG) and thyroperoxidase (TPO) in
most of the patients with autoimmune thyroid disease is now well documented. Studies of …

Thyrotropin receptor antibodies: advances and importance of detection techniques in thyroid diseases

MK Gupta - Clinical biochemistry, 1992 - Elsevier
The study of autoimmune thyroid disorders (AITD) has greatly contributed to our knowledge
of autoimmunity. Graves' disease and Hashimoto's thyroiditis represent two ends of the …

Thyrotropin-receptor antibodies in thyroid diseases: advances in detection techniques and clinical applications

MK Gupta - Clinica Chimica Acta, 2000 - Elsevier
Thyroid disorders are the most common autoimmune endocrinopathies. Thyroid
autoimmunity is complex, involving multiple autoantigens with variable immune responses …

Clinical and laboratory aspects of thyroid autoantibodies

D Sinclair - Annals of clinical biochemistry, 2006 - journals.sagepub.com
This review describes the aetiology of the major thyroid antigens. Iodination of thyroglobulin
produces multiple antigen configurations which are functionally active but immunologically …

Clinical review about TRAb assay's history

K Zöphel, D Roggenbuck, M Schott - Autoimmunity reviews, 2010 - Elsevier
Commercial assays to measure thyroid stimulating hormone (TSH) receptor (TSHR)
autoantibodies (TRAb) have been available for the serological diagnosis of autoimmune …