A reflectance spectroscopic device that utilizes a single fiber for both light delivery and
collection has advantages over classical multi-fiber probes. This study presents a novel …

We are reporting on an experimental investigation of a movable diffuse reflectance
spectroscopy system to extract diagnostically relevant optical properties of two-layered …

Light propagation models often simplify the interface between the optical fiber probe tip and
tissue to a laterally uniform boundary with mismatched refractive indices. Such simplification …

Spectral reflectance measurements of biological tissues have been studied for early
diagnoses of several pathologies such as cancer. These measurements are often performed …

Diffuse reflectance spectroscopy with a fiber optic probe is a powerful tool for quantitative
tissue characterization and disease diagnosis. Significant systematic errors can arise in the …

Optical biopsy has been shown to discriminate between normal and diseased tissue with
high sensitivity and specificity. Fiber-optic probe-based spectroscopy systems do not provide …

Calibration of the diffuse reflectance spectrum for instrument response and time-dependent
fluctuation as well as interdevice variations is complicated, time consuming, and potentially …

We present the design and construction of a fiber optic probe for elastic light scattering
spectroscopy in vivo with polarized excitation and polarization sensitive detection. The …

We have recently demonstrated a means for quantifying the absorption and scattering
properties of biological tissue through multidiameter single-fiber reflectance (MDSFR) …

The goal of the work is to experimentally verify Monte Carlo modeling of fluorescence and
diffuse reflectance measurements in turbid, tissue phantom models. In particular, two series …