Spatially resolved reflectance spectroscopy<? xpp qa?> for diagnosis of cervical precancer: Monte Carlo modeling and comparison to clinical measurements

D Arifler, C MacAulay, M Follen… - … of Biomedical Optics, 2006 - spiedigitallibrary.org
We present Monte Carlo modeling studies to provide a quantitative understanding of
contrast observed in spatially resolved reflectance spectra of normal and highly dysplastic …

Optical sectioning using a fiber probe with an angled illumination-collection geometry: evaluation in engineered tissue phantoms

L Nieman, A Myakov, J Aaron, K Sokolov - Applied optics, 2004 - opg.optica.org
We present a fiber optic probe that combines polarized illumination and detection with an
angled distal probe geometry to detect the size-dependent scattering at a specific depth …

Optical sampling depth in the spatial frequency domain

CK Hayakawa, K Karrobi, V Pera… - … of biomedical optics, 2019 - spiedigitallibrary.org
We present a Monte Carlo (MC) method to determine depth-dependent probability
distributions of photon visitation and detection for optical reflectance measurements …

The determination of in vivo human tissue optical properties and absolute chromophore concentrations using spatially resolved steady-state diffuse reflectance …

RMP Doornbos, R Lang, MC Aalders… - Physics in Medicine …, 1999 - iopscience.iop.org
A method is described for measuring optical properties and deriving chromophore
concentrations from diffuse reflection measurements at the surface of a turbid medium. The …

Validity of the semi-infinite tumor model in diffuse reflectance spectroscopy for epithelial cancer diagnosis: a Monte Carlo study

C Zhu, Q Liu - Optics Express, 2011 - opg.optica.org
The accurate understanding of optical properties of human tissues plays an important role in
the optical diagnosis of early epithelial cancer. Many inverse models used to determine the …

Simple two-layer reflectance model for biological tissue applications

G Mantis, G Zonios - Applied optics, 2009 - opg.optica.org
A two-layer tissue diffuse reflectance model is described. The model is based on a simple
one-layer model that we have recently developed and successfully applied to the analysis of …

Lookup table–based inverse model for determining optical properties of turbid media

N Rajaram, TH Nguyen… - Journal of biomedical …, 2008 - spiedigitallibrary.org
We present a lookup table (LUT)–based inverse model for determining the optical properties
of turbid media from steady-state diffuse reflectance spectra that is valid for fiber-based …

In vivo determination of optical properties of normal and tumor tissue with white light reflectance and an empirical light transport model during endoscopy

PR Bargo, SA Prahl, TT Goodell… - … of biomedical optics, 2005 - spiedigitallibrary.org
Determination of tissue optical properties is fundamental for application of light in either
therapeutical or diagnostics procedures. In the present work we implemented a spatially …

Combined Monte Carlo and finite-difference time-domain modeling for biophotonic analysis: implications on reflectance-based diagnosis of epithelial precancer

C Kortun, YR Hijazi, D Arifler - Journal of Biomedical Optics, 2008 - spiedigitallibrary.org
Monte Carlo (MC) modeling of photon transport in tissues is generally performed using
simplified functions that only approximate the angular scattering properties of tissue …

Illumination and fluorescence collection volumes for fiber optic probes in tissue

DCS Tai, DA Hooks, JD Harvey… - … of biomedical optics, 2007 - spiedigitallibrary.org
Optical fibers can deliver light to, and collect it from, regions deep in tissue. However,
reported illumination and fluorescence collection volumes adjacent to the fiber tip have been …