Purpose: It has been reported that CO 2 gas, used to establish a pneumoperitoneum during
laparoscopy, affects the behavior of tumor cells. The proto-oncogenes c-myc and HMGB-1 …

Background: Minimally invasive techniques are increasingly applied to children with
malignant tumors. We showed previously that CO 2 used for pneumoperitoneum modulates …

Background The response of mesothelial cells to surgical trauma and bacterial
contamination is poorly defined. We have recently shown that CO 2 pneumoperitoneum …

Purpose We evaluated in vitro the role of CO 2-induced oxidative stress on the expression of
proteins involved in cell-cycle regulation of neuroblastoma cells. Methods SH-SY5Y cells …

Purpose Several oxygen-dependent factors, eg, CAIX (carbonic anhydrase IX) or
phosphoglycerate kinase 1 (PGK1) interacting with the CXCR4/SDF1 axis (chemokine …

Background/Purpose: Aggressive tumors may alter their expression of Bcl-2 proteins to
decrease apoptosis and increase survival. The authors reported previously that …

Background Minimally invasive techniques are increasingly used for biopsy and resection of
neuroblastoma, but the impact on the behavior of spilled tumor cells is unknown. We aimed …

Objective To understand the effects of HMGB1 recombinant lentivirus vector on proliferation
and apoptosis on CD133 cells after transfecting a human glioma cell strain CD133. Method …

The effects and potential molecular mechanisms underlying carbon dioxide (CO 2)
pneumoperitoneum on gastric cancer cell apoptosis are not fully understood. In this study …

Hypoxia is an important factor in the macrophages microenvironment. Many physiological
and pathological processes including solid tumor development are characterized by both …