Purpose: The purpose of this study was to determine the incidence of c-Myc protein
expression in medulloblastoma/primititive neuroectodermal tumor (MB/PNET) and to identify …

H igh M obility G roup B ox1 protein (HMGB1), one of the mediators of inflammation, is
associated with tumorigenesis. The HMGB1‐Receptor for advanced glycation end‐products …

Background Novel strategies are required since the hypoxic tumor microenvironment is one
of the important impediments for conventional cancer therapy. High mobility group box 1 …

Background: The human high mobility group protein B1 (HMGB1) has attracted
considerable interest among oncologists because it sensitises cancer cells to the anticancer …

The HMGB1 protein has multiple functions in tumor biology and can act both as a
transcription factor and as a cytokine. HMGB1 is released during cell death, and in our …

Background Dying tumor cells after irradiation could promote the proliferation of living tumor
cells might cause tumor relapse and treatment failure. Our previous study showed that …

Background To study whether and how c-MYC expression determines response to radio-
and chemotherapy in childhood medulloblastoma (MB). Methods We used DAOY and …

Pyroptosis, a newly discovered mode of programmed cell death (PCD), is important in the
regulation of cancer development. High mobility group box 1 (HMGB1) is a non-histone …

Background: Cytoglobin (Cygb) was first described in 2002 as an intracellular globin of
unknown function. We have previously shown the downregulation of cytoglobin as a key …

Bcl-2 protooncogene, originally discovered at the chromosomal breakpoint of the t (14; 18)
in follicular lymphoma, is known to regulate the process of programmed cell death or …