Expression of the c-Myc protein in childhood medulloblastoma
CS Bruggers, KF Tai, T Murdock, L Sivak… - Journal of pediatric …, 1998 - journals.lww.com
Purpose: The purpose of this study was to determine the incidence of c-Myc protein
expression in medulloblastoma/primititive neuroectodermal tumor (MB/PNET) and to identify …
expression in medulloblastoma/primititive neuroectodermal tumor (MB/PNET) and to identify …
H igh M obility G roup B ox1 (HMGB1) released from cancer cells induces the expression of pro‐inflammatory cytokines in peritoneal fibroblasts
A Abe, T Kuwata, C Yamauchi, Y Higuchi… - Pathology …, 2014 - Wiley Online Library
H igh M obility G roup B ox1 protein (HMGB1), one of the mediators of inflammation, is
associated with tumorigenesis. The HMGB1‐Receptor for advanced glycation end‐products …
associated with tumorigenesis. The HMGB1‐Receptor for advanced glycation end‐products …
[HTML][HTML] Cell type-specific response of colon cancer tumor cell lines to oncolytic HSV-1 virotherapy in hypoxia
Background Novel strategies are required since the hypoxic tumor microenvironment is one
of the important impediments for conventional cancer therapy. High mobility group box 1 …
of the important impediments for conventional cancer therapy. High mobility group box 1 …
Expression pattern of the HMGB1 gene in sarcomas of the dog
B Meyer, HM Escobar, S Hauke, A Richter… - Anticancer …, 2004 - ar.iiarjournals.org
Background: The human high mobility group protein B1 (HMGB1) has attracted
considerable interest among oncologists because it sensitises cancer cells to the anticancer …
considerable interest among oncologists because it sensitises cancer cells to the anticancer …
[HTML][HTML] The HMGB1 protein sensitizes colon carcinoma cells to cell death triggered by pro-apoptotic agents
CC Zhang, G Gdynia… - … journal of oncology, 2015 - spandidos-publications.com
The HMGB1 protein has multiple functions in tumor biology and can act both as a
transcription factor and as a cytokine. HMGB1 is released during cell death, and in our …
transcription factor and as a cytokine. HMGB1 is released during cell death, and in our …
[HTML][HTML] Increased HMGB1 and cleaved caspase-3 stimulate the proliferation of tumor cells and are correlated with the poor prognosis in colorectal cancer
Z Zhang, M Wang, L Zhou, X Feng, J Cheng… - Journal of Experimental …, 2015 - Springer
Background Dying tumor cells after irradiation could promote the proliferation of living tumor
cells might cause tumor relapse and treatment failure. Our previous study showed that …
cells might cause tumor relapse and treatment failure. Our previous study showed that …
[HTML][HTML] c-MYC expression sensitizes medulloblastoma cells to radio-and chemotherapy and has no impact on response in medulloblastoma patients
AO von Bueren, C Oehler, T Shalaby, K von Hoff… - BMC cancer, 2011 - Springer
Background To study whether and how c-MYC expression determines response to radio-
and chemotherapy in childhood medulloblastoma (MB). Methods We used DAOY and …
and chemotherapy in childhood medulloblastoma (MB). Methods We used DAOY and …
[HTML][HTML] Endogenous HMGB1 regulates GSDME-mediated pyroptosis via ROS/ERK1/2/caspase-3/GSDME signaling in neuroblastoma
CY Fan, FH Ye, M Peng, JJ Dong… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Pyroptosis, a newly discovered mode of programmed cell death (PCD), is important in the
regulation of cancer development. High mobility group box 1 (HMGB1) is a non-histone …
regulation of cancer development. High mobility group box 1 (HMGB1) is a non-histone …
[HTML][HTML] Cytoglobin is upregulated by tumour hypoxia and silenced by promoter hypermethylation in head and neck cancer
RJ Shaw, MM Omar, S Rokadiya, FA Kogera… - British journal of …, 2009 - nature.com
Background: Cytoglobin (Cygb) was first described in 2002 as an intracellular globin of
unknown function. We have previously shown the downregulation of cytoglobin as a key …
unknown function. We have previously shown the downregulation of cytoglobin as a key …
Bcl-2 oncoprotein expression and apoptosis in neuroblastoma
H Ikeda, J Hirato, M Akami, S Matsuyama… - Journal of Pediatric …, 1995 - Elsevier
Bcl-2 protooncogene, originally discovered at the chromosomal breakpoint of the t (14; 18)
in follicular lymphoma, is known to regulate the process of programmed cell death or …
in follicular lymphoma, is known to regulate the process of programmed cell death or …