Background: Peritoneal carcinomatosis (PC) arising from colorectal cancer is associated
with poor prognosis and few treatment options are currently available. Laparoscopic CO2 …

The growth factor hepatocyte growth factor (HGF), also known as scatter factor, and its
tyrosine kinase receptor c-Met play important roles in medulloblastoma malignancy. The …

Cancer cells produce energy through aerobic glycolysis, but contributions of host tissues to
cancer energy metabolism are unclear. In this study, we aimed to elucidate the cancer–host …

In human glioma tumours, heme oxygenase-1 (HO-1) is overexpressed when compared
with normal brain tissues and during oligodendroglioma progression. However, the …

Background: Recently, it has become obvious that the HMGB1 protein can act as a
proinflammatory and proangiogenic mediator when actively secreted by macrophages or …

Most neuroblastomas with N-myc amplification, a sign of extremely poor prognosis, are
extensively invasive to surrounding tissues. Therefore, we investigated the relationship …

Neuroblastoma (NB) is the most common and deadliest extracranial solid tumor in children.
Targeting tumor-associated macrophages (TAMs) is a strategy for attenuating tumor …

The c-MYC protein participates in energy-consuming processes such as proliferation and
ribosome biosynthesis, and its expression is often dysregulated in human cancers. Cancer …

AIM: To investigate the effects of carbon dioxide (CO 2) and helium insufflation administered
at different pressures on the growth and apoptosis of cultured human gastric cancer cells …

Colorectal cancer is the second leading cause of death in developed countries. Tumor
therapies should on the one hand aim to stop the proliferation of tumor cells and to kill them …