Hedgehog signaling pathway in neuroblastoma differentiation
R Souzaki, T Tajiri, M Souzaki, Y Kinoshita… - Journal of pediatric …, 2010 - Elsevier
PURPOSE: The hedgehog (Hh) signaling pathway is activated in some adult cancers. On
the other hand, the Hh signaling pathway plays an important role in the development of the …
the other hand, the Hh signaling pathway plays an important role in the development of the …
Hypoxia can induce c‐Met expression in glioma cells and enhance SF/HGF‐induced cell migration
C Eckerich, S Zapf, R Fillbrandt, S Loges… - … journal of cancer, 2007 - Wiley Online Library
The c‐Met receptor and its ligand scatter factor/hepatocyte growth factor (SF/HGF) are
strongly overexpressed in malignant gliomas. Signaling through c‐Met as well as exposure …
strongly overexpressed in malignant gliomas. Signaling through c‐Met as well as exposure …
The effect of N-myc amplification and expression on invasiveness of neuroblastoma cells
Y Zaizen, S Taniguchi, S Noguchi, S Suita - Journal of pediatric surgery, 1993 - Elsevier
Most neuroblastomas with N-myc amplification, a sign of extremely poor prognosis, are
extensively invasive to surrounding tissues. Therefore, we investigated the relationship …
extensively invasive to surrounding tissues. Therefore, we investigated the relationship …
Serum HMGB1 as a prognostic marker for malignant pleural mesothelioma
C Tabata, E Shibata, R Tabata, S Kanemura, K Mikami… - BMC cancer, 2013 - Springer
Background Malignant pleural mesothelioma (MPM) is an aggressive malignant tumor of
mesothelial origin that shows a limited response to conventional chemotherapy and …
mesothelial origin that shows a limited response to conventional chemotherapy and …
Upregulation of HMGB1 in tumor-associated macrophages induced by tumor cell-derived lactate further promotes colorectal cancer progression
X Gao, S Zhou, Z Qin, D Li, Y Zhu, D Ma - Journal of Translational …, 2023 - Springer
Background Lactate accumulation leads to an acidic tumor microenvironment (TME), in turn
promoting colorectal cancer (CRC) progression. Tumor-associated macrophages (TAMs) …
promoting colorectal cancer (CRC) progression. Tumor-associated macrophages (TAMs) …
Aggressive childhood neuroblastomas do not express caspase-8: an important component of programmed cell death
T Teitz, JM Lahti, VJ Kidd - Journal of molecular medicine, 2001 - Springer
Neuroblastomas that overexpress N-Myc due to amplification of the MYCN oncogene are
aggressive tumors that become very resistant to treatment by chemotherapy and irradiation …
aggressive tumors that become very resistant to treatment by chemotherapy and irradiation …
Changes in CO2 concentration increase the invasive ability of colon cancer cells
S Obata, T Goi, T Nakazawa, Y Kimura… - Anticancer …, 2013 - ar.iiarjournals.org
Background/Aim: We studied the effects of CO2 concentration changes on the invasive
ability of colon cancer cells. Materials and Methods: Colon cancer cell lines and human …
ability of colon cancer cells. Materials and Methods: Colon cancer cell lines and human …
Effects of HMGB1 on PMN apoptosis during LPS-induced acute lung injury
Y Feng, Q Yang, J Xu, G Qian, Y Liu - Experimental and molecular …, 2008 - Elsevier
OBJECTIVE: To observe the effects of intravenous injection of HMGB1 inhibitor sodium
butyrate on changes in apoptosis of PMN during LPS-induced acute lung injury in rats and …
butyrate on changes in apoptosis of PMN during LPS-induced acute lung injury in rats and …
Mesenchymal-epithelial signalling in tumour microenvironment: role of high-mobility group Box 1
S Sharma, A Evans, E Hemers - Cell and tissue research, 2016 - Springer
Glucose deprivation, hypoxia and acidosis are characteristic features of the central core of
most solid tumours. Myofibroblasts are stromal cells present in many such solid tumours …
most solid tumours. Myofibroblasts are stromal cells present in many such solid tumours …
Sublethal irradiation promotes invasiveness of neuroblastoma cells
L Schweigerer, M Rave-Fränk, H Schmidberger… - Biochemical and …, 2005 - Elsevier
Neuroblastoma is the most frequent extracranial solid tumour of childhood. Despite multiple
clinical efforts, clinical outcome has remained poor. Neuroblastoma is considered to be …
clinical efforts, clinical outcome has remained poor. Neuroblastoma is considered to be …