Object Medulloblastoma (MB) is the most common malignant brain tumor in children. Heat
shock proteins (HSPs) comprise a superfamily of proteins that serve as molecular …

Background/Purpose: Patients who have neuroblastomas with N-myc amplification that are
extremely invasive and result in distant metastases tend to have a very poor prognosis. The …

BACKGROUND: The expression of caspase-8, a cysteine protease that is crucial for the
apoptotic cascade, is absent in a high percentage of neuroblastomas, the most frequent …

Background: Whether laparoscopy with CO 2 pneumoperitoneum affects the peritoneal
metastasis of gastric cancer is a pressing question. In light of the important impact change in …

The present study explored the inhibitory effect of hyperthermic CO2 pneumoperitoneum on
the proliferation and migration of colon cancer cells, and its mechanism. Colon cancer cell …

Background. The dysregulation of apoptosis may alter the progression of tumor growth and
explain the clinical dichotomy observed in children with neuroblastoma (NB). An …

Radiotherapy (RT) is a traditional and important treatment for carcinoma of the esophagus
along with surgery and chemotherapy. High mobility group box 1 (HMGB1) plays a crucial …

Background Conventional laparoscopic surgery uses CO 2 that is dry and cold, which can
damage peritoneal surfaces. It is speculated that disseminated cancer cells may adhere to …

Background Neuroblastoma is the most common extracranial solid tumor of childhood. The
heterogeneous microenvironment of solid tumors contains hypoxic regions associated with …

Human malignant mesothelioma (MM) is an aggressive cancer linked to asbestos and
erionite exposure. We previously reported that High-Mobility Group Box-1 protein (HMGB1) …