Hedgehog pathway activity in pediatric embryonal rhabdomyosarcoma and undifferentiated sarcoma: a report from the Children's Oncology Group
JG Pressey, JR Anderson, DK Crossman… - Pediatric blood & …, 2011 - Wiley Online Library
Background Aberrant activation of the hedgehog (Hh) signaling pathway is implicated
widely in both pediatric and adult malignancies. Inactivation of the Hh regulator PTCH is …
widely in both pediatric and adult malignancies. Inactivation of the Hh regulator PTCH is …
Tumor hypoxia and expression of c-met in cervical cancer
C Leo, LC Horn, J Einenkel, B Hentschel… - Gynecologic oncology, 2007 - Elsevier
OBJECTIVES: Hypoxia enhances malignant progression by promoting the development of
metastases and increasing invasiveness. One key regulator that controls growth, invasion …
metastases and increasing invasiveness. One key regulator that controls growth, invasion …
HMGB1 knock‐down promoting tumor cells viability and arrest pro‐apoptotic proteins via Stat3/NFκB in HepG2 cells
S Alduais, Y Alduais, X Wu, H Li, J Mao - Biofactors, 2018 - Wiley Online Library
Abstract Background/Aim: High mobility group box 1 protein (HMGB1) is functionally
dynamic and pleiotropic molecule, it has the potential to promote both cell survival and …
dynamic and pleiotropic molecule, it has the potential to promote both cell survival and …
Carbonic anhydrase II: a novel biomarker for pseudomyxoma peritonei
P Järvinen, AJ Kivelä, P Nummela, A Lepistö… - Apmis, 2017 - Wiley Online Library
Altered expression of carbonic anhydrase (CA) II is associated with human carcinogenesis.
We analysed CA II protein expression in 89 patients with pseudomyxoma peritonei (PMP) …
We analysed CA II protein expression in 89 patients with pseudomyxoma peritonei (PMP) …
Up-regulated HMGB1 in the pleural effusion of non-small cell lung cancer (NSCLC) patients reduces the chemosensitivity of NSCLC cells
Y Ma, S Kang, X Wu, B Han, Z Jin, Z Guo - Tumori Journal, 2018 - journals.sagepub.com
Background: Pleural effusion is one of the complications of human non-small cell lung
cancer (NSCLC). High mobility group box-1 protein (HMGB1) correlates highly with invasion …
cancer (NSCLC). High mobility group box-1 protein (HMGB1) correlates highly with invasion …
Knockdown of HMGB1 suppresses hypoxia-induced mitochondrial biogenesis in pancreatic cancer cells
L Yang, F Ye, L Zeng, Y Li, W Chai - OncoTargets and therapy, 2020 - Taylor & Francis
Purpose To explore the regulatory effect of HMGB1 upon hypoxia-induced mitochondrial
biogenesis in pancreatic cancer PANC1/CFPAC1 cells. Methods After a down-regulation of …
biogenesis in pancreatic cancer PANC1/CFPAC1 cells. Methods After a down-regulation of …
[PDF][PDF] Knockdown of HMGB2 inhibits proliferation and invasion of renal tumor cells via the p-38MAPK pathway.
ZH He, F Guo, XX Hu, ZY Luo… - European Review for …, 2020 - europeanreview.org
OBJECTIVE: To investigate the function of HMGB2 in renal tumor ACHN cells in vitro and in
vivo and to study the underlying molecular mechanisms. PATIENTS AND METHODS …
vivo and to study the underlying molecular mechanisms. PATIENTS AND METHODS …
Human neuroblastoma cells exposed to hypoxia: induction of genes associated with growth, survival, and aggressive behavior
A Jögi, J Vallon-Christersson, L Holmquist… - Experimental cell …, 2004 - Elsevier
We have recently found that cells derived from human neuroblastoma, a sympathetic
nervous system (SNS) tumor, dedifferentiate and acquire a neural crest-like phenotype …
nervous system (SNS) tumor, dedifferentiate and acquire a neural crest-like phenotype …
Reoxygenation using a novel CO2 therapy decreases the metastatic potential of osteosarcoma cells
R Harada, T Kawamoto, T Ueha, M Minoda… - Experimental cell …, 2013 - Elsevier
Osteosarcoma is the most common primary solid malignant bone tumor. Despite substantial
improvements in surgery and chemotherapy, metastasis remains a major cause of fatal …
improvements in surgery and chemotherapy, metastasis remains a major cause of fatal …
HMGB1 promotes HCC progression partly by downregulating p21 via ERK/c-Myc pathway and upregulating MMP-2
Y Chen, C Lin, Y Liu, Y Jiang - Tumor Biology, 2016 - Springer
High-mobility group box 1 (HMGB1) was found to be over-expressed in many kinds of
human cancer, which binds with several receptors and activates RAGE-Ras-MAPK, Toll-like …
human cancer, which binds with several receptors and activates RAGE-Ras-MAPK, Toll-like …