Harnessing the regenerative capabilities of endogenous precursor cells in the spinal cord
may be a useful tool for clinical treatments aimed at replacing cells lost as a consequence of …

Endogenous cell proliferation and gliogenesis have been extensively documented in spinal
cord injury, particularly in terms of proliferating oligodendrocyte progenitor cells. Despite the …

Spinal cord injury (SCI) results in motor and sensory deficits, the severity of which depends
on the level and extent of the injury. Animal models for SCI research include transection …

The adult mammalian spinal cord contains neural stem and/or progenitor cells that slowly
multiply throughout life and differentiate exclusively into glia. The contribution of adult …

Spinal cord injury (SCI) is a devastating disorder that has a poor prognosis of recovery.
Animal models of SCI are useful to understand the pathophysiology of SCI and the potential …

BACKGROUND: Spinal cord injury (SCI) is a common and often irreversible lesion that can
incapacitate patients. Precursor cells in the spinal cord proliferate in response to trauma …

Traumatic injury to the adult spinal cord results in a massive loss of cells and permanent
functional deficits. However, recent studies demonstrate that there is a proliferative response …

Background There are multiple promising treatment strategies for central nervous system
trauma and disease. However, to develop clinically potent and safe treatments, models of …

Stem/progenitor cells derived from the ependymal region of the spinal cord have the ability
to self-renew and are multipotential for neurons and glia. These cells may have the ability to …

Spinal cord injury (SCI) has been regarded clinically as an irreversible damage caused by
tissue contusion due to a blunt external force. Past research had focused on the analysis of …