Granulocyte-macrophage colony-stimulating factor and the neutrophil: mechanisms of action

J Gomez-Cambronero, RI Sha'afi - Cell-Cell Interactions in the Release of …, 1991 - Springer
The granulocyte-macrophage colony-stimulating factor (GM-CSF) is a hemopoietic growth
factor that regulates the production and functional activity of granulocytes and macrophages …

The biology of granulocyte-macrophage colony-stimulating factor: effects on hematopoietic and nonhematopoietic cells

GC Baldwin - Developmental Biology, 1992 - Elsevier
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of a family of
glycoprotein cytokines that have potent effects in stimulating the proliferation, maturation …

Granulocyte colony-stimulating factor

T Kato - Handbook of hormones, 2021 - Elsevier
This chapter discusses granulocyte colony-stimulating factor, which is the primary regulator
of proliferation and differentiation, maturation, survival, and functions of neutrophils …

Granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF): receptor biology, signal transduction, and neutrophil …

AP Rapoport, CN Abboud, JF DiPersio - Blood reviews, 1992 - Elsevier
Granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-
stimulating factor (G-CSF) are two of the growing number of recognized cytokines involved …

Granulocyte-macrophage colony-stimulating factor is a chemoattractant cytokine for human neutrophils: involvement of the ribosomal p70 S6 kinase signaling …

J Gomez-Cambronero, J Horn, CC Paul… - The Journal of …, 2003 - journals.aai.org
GM-CSF stimulates proliferation of myeloid precursors in bone marrow and primes mature
leukocytes for enhanced functionality. We demonstrate that GM-CSF is a powerful …

Granulocyte colony-stimulating factor: molecular mechanisms of action during steady state and 'emergency'hematopoiesis

AD Panopoulos, SS Watowich - Cytokine, 2008 - Elsevier
Neutrophils are phagocytes whose principal function is to maintain anti-bacterial immunity.
Neutrophils ingest and kill invading bacteria, releasing cytotoxic, chemotactic and …

The nature and action of granulocyte-macrophage colony stimulating factors

AW Burgess, D Metcalf - 1980 - ashpublications.org
Granulocyte-macrophage colony stimulating factor (GM-CSF) stimulates the in vitro
proliferation and differentiation of granulocytic and macrophage cells. This regulator is now …

Mini ReviewGM-CSF Biology

JA Hamilton, GP Anderson - Growth factors, 2004 - Taylor & Francis
Granulocyte macrophage-colony stimulating factor (GM-CSF) was originally defined by its
ability to generate in vitro granulocyte and macrophage colonies from bone marrow …

Secretion of colony-stimulating factor for macrophages (M-CSF) and granulocyte/macrophages (GM-CSF) is developmentally regulated in human macrophages

C Scheibenbogen, G Zenke, B Faggs… - … , oncology, and AIDS, 1990 - Springer
Cells of the mononuclear phagocyte system (MPS) are involved in the immune surveillance
against microbial pathogens and malignant cells but are also important regulator cells in …

Granulocyte colony-stimulating factor induces neutrophils to secrete macrophage colony-stimulating factor

E Santiago, L Mora, M Bautista, JJ Montesinos… - Cytokine, 2001 - Elsevier
In this work we provide evidence showing that granulocytes produce macrophage colony-
stimulating factor (M-CSF) from the band cell stage and secrete this factor when induced to …