Modulatory effects of 17β-estradiol on acute lung inflammation after total occlusion of the descending aorta in male rats

LF da Anunciação, MN de Sousa… - International …, 2022 - Elsevier
As a consequence of systemic inflammation caused by ischemia and reperfusion (I/R) due to
aortic occlusion, the lungs can exhibit increased microvascular permeability, local release of …

Evaluation of the therapeutic effects of oestradiol on the systemic inflammatory response and on lung injury caused by the occlusion of the proximal descending aorta …

MN de Sousa, LF da Anunciação… - European Journal of …, 2023 - academic.oup.com
OBJECTIVES Ischaemia and reperfusion-induced microvascular dysfunction is a serious
problem encountered during a variety surgical procedures, leading to systemic inflammation …

Acute effects of estradiol on lung inflammation due to intestinal ischemic insult in male rats

AC Breithaupt-Faloppa, ET Fantozzi, DC Romero… - Shock, 2014 - journals.lww.com
Intestinal ischemia and reperfusion (intestinal I/R) causes acute lung inflammation that is
characterized by leukocyte migration, increased lung microvascular permeability, and, in …

Protective effect of estradiol on acute lung inflammation induced by an intestinal ischemic insult is dependent on nitric oxide

AC Breithaupt-Faloppa, ET Fantozzi, MM Assis-Ramos… - Shock, 2013 - journals.lww.com
Introduction: It has been shown that the innate immune system mediates acute lung
inflammation triggered by intestinal trauma. Sexual dimorphism modulates the profile of TH …

Estrogen ameliorates sepsis-induced vascular hyporeactivity in thoracic aorta of female rats via permissive effect of GRα expression

S Wang, J Wu, K Yang, C Liu, X Li, L Wu, X Qi… - Biochemical and …, 2023 - Elsevier
Objective Estrogen is correlated to the lower mortality and disease severity of female than
that of male, which indicates the potential therapeutic role of estrogen supplement therapy in …

[HTML][HTML] 17β-Estradiol prevents mesenteric injury induced by occlusion of the proximal descending aorta in male rats

PTR de Sousa, AC Breithaupt-Faloppa… - Journal of vascular …, 2018 - Elsevier
Objective In surgical aortic repair or cardiac surgery with aorta occlusion, the occurrence of
mesenteric ischemia and bowel injury has been associated with higher short-term mortality …

Estradiol mediates the long-lasting lung inflammation induced by intestinal ischemia and reperfusion

ET Fantozzi, AC Breithaupt-Faloppa… - Journal of Surgical …, 2018 - Elsevier
Background Lung inflammation is one of the main consequences of intestinal ischemia
reperfusion (intestinal IR) and, in severe cases, can lead to acute respiratory distress …

Acute lung injury induced by intestinal ischemia and reperfusion is altered in obese female mice

ET Fantozzi, S Rodrigues-Garbin… - Pulmonary …, 2018 - Elsevier
Rational Acute lung injury (ALI) is a common complication after intestinal ischemia and
reperfusion (I/R) injury that can lead to acute respiratory distress syndrome (ARDS). We …

High Dose of Estrogen Protects the Lungs from Ischemia–Reperfusion Injury by Downregulating the Angiotensin II Signaling Pathway

P Dai, J He, Y Wei, M Xu, J Zhao, X Zhou, H Tang - Inflammation, 2024 - Springer
We explored the sex difference in lung ischemia–reperfusion injury (LIRI) and the role and
mechanism of estrogen (E2) and angiotensin II (Ang II) in LIRI. We established a model of …

2-Methoxyestradiol protects against lung ischemia/reperfusion injury by upregulating annexin A1 protein expression

WI Liao, SY Wu, SH Tsai, HP Pao, KL Huang… - Frontiers in …, 2021 - frontiersin.org
Background: 2-Methoxyestradiol (2ME), a natural 17-β estradiol metabolite, is a potent anti-
inflammatory agent, but its effect on ischemia/reperfusion (IR)-induced acute lung …