Background Recent achievement in genetics and epigenetics has led to the exploration of
the pathogenesis of systemic lupus erythematosus (SLE). Identification of differentially …

Epigenetic regulation of immune cell types could be critical for the development and
maintenance of autoimmune diseases like rheumatoid arthritis (RA). B cells are highly …

Objectives Epigenetics can influence disease susceptibility and severity. While DNA
methylation of individual genes has been explored in autoimmunity, no unbiased systematic …

Rheumatoid arthritis (RA) is a complex chronic systematic disease with progressive
destruction of the joints by invasive synoviocytes. To characterize the key regulators …

Objective Primary Sjögren's syndrome (SS) is a systemic autoimmune disease with
incompletely understood etiology. This study was undertaken to investigate the role of …

Objectives Systemic lupus erythematosus (SLE) is a chronic autoimmune condition with
heterogeneous presentation and complex aetiology where DNA methylation changes are …

The etiology of systemic lupus erythematosus (SLE) involves a complex interaction of
genetic and environmental factors. Investigations have shown that environmentally driven …

Background Systemic lupus erythematosus (SLE) is the prototypic systemic autoimmune
disease. Genome‐wide (GW) association studies have identified more than 40 disease …

Systemic lupus erythematosus (SLE or lupus) is a heterogeneous autoimmune disease
characterized by the involvement of multiple organs and the production of antinuclear …

Objectives To identify novel DNA methylation sites significant for rheumatoid arthritis (RA)
and comprehensively understand their underlying pathological mechanism. Methods We …