Determinants of virological failure and antiretroviral drug resistance in Mozambique

M Rupérez, C Pou, S Maculuve… - Journal of …, 2015 - academic.oup.com
Objectives The objective of this study was to inform public health actions to limit first-line
ART failure and HIV drug resistance in Mozambique. Methods This was a cross-sectional …

Rate and predictors of HIV virological failure among adults on first-line antiretroviral treatment in Dar Es Salaam, Tanzania

FG Samizi, OD Panga, SS Mulugu, CG Gitige… - The Journal of Infection …, 2021 - jidc.org
Introduction: Monitoring resistance to first line Antiretroviral therapy (ART) is crucial in
preventing accumulation of viral mutations following the implementation of the World Health …

Virological outcome and patterns of HIV‐1 drug resistance in patients with 36 months' antiretroviral therapy experience in Cameroon

AF Aghokeng, C Kouanfack… - Journal of the …, 2013 - Wiley Online Library
Introduction The current expansion of antiretroviral treatment (ART) in the developing world
without routine virological monitoring still raises concerns on the outcome of the strategy in …

HIV virological failure and drug resistance in a cohort of Tanzanian HIV-infected adults

C Hawkins, N Ulenga, E Liu, S Aboud… - Journal of …, 2016 - academic.oup.com
Objectives There are few data on ART failure rates and drug resistance from Tanzania,
where there is a wide diversity of non-B HIV subtypes. We assessed rates and predictors of …

Nationwide estimates of viral load suppression and acquired HIV drug resistance in Cameroon

GF Tchouwa, S Eymard-Duvernay, A Cournil… - …, 2018 - thelancet.com
Background Population-based studies to estimate viral load (VL) suppression and rate of
acquired HIV drug resistance (ADR) are essential in sub-Saharan Africa. We conducted the …

Virological failure after 1 year of first-line ART is not associated with HIV minority drug resistance in rural Cameroon

A Zoufaly, J Jochum, R Hammerl… - Journal of …, 2015 - academic.oup.com
Objectives The aim of this study was to describe clinical and virological outcomes in therapy-
naive HIV-1-positive patients treated in a routine ART programme in rural Cameroon …

Virologic failure and human immunodeficiency virus drug resistance in rural Cameroon with regard to the UNAIDS 90-90-90 treatment targets

C Boullé, E Guichet, C Kouanfack… - Open Forum …, 2016 - academic.oup.com
Abstract Background In rural Africa, data on virologic effectiveness of antiretroviral treatment
(ART) are not sufficient to assess the gap with the UNAIDS 90-90-90 treatment targets. We …

Strengthening HIV therapy and care in rural Tanzania affects rates of viral suppression

AJ Ntamatungiro, L Muri, TR Glass, S Erb… - Journal of …, 2017 - academic.oup.com
Objectives: To assess viral suppression rates, to assess prevalence of acquired HIV drug
resistance and to characterize the spectrum of HIV-1 drug resistance mutations (HIV-DRM) …

HIV-1 virologic failure and acquired drug resistance among first-line antiretroviral experienced adults at a rural HIV clinic in coastal Kenya: a cross-sectional study

AS Hassan, HM Nabwera, SM Mwaringa… - AIDS research and …, 2014 - Springer
Background An increasing number of people on antiretroviral therapy (ART) in sub-Saharan
Africa has led to declines in HIV related morbidity and mortality. However, virologic failure …

Development of HIV drug resistance and therapeutic failure in children and adolescents in rural Tanzania: an emerging public health concern

L Muri, A Gamell, AJ Ntamatungiro, TR Glass… - Aids, 2017 - journals.lww.com
Objective: To investigate the prevalence and determinants of virologic failure and acquired
drug resistance-associated mutations (DRMs) in HIV-infected children and adolescents in …