Engagement of diverse protein ligands (MIC-A/B, ULBP, Rae-1, or H60) by NKG2D
immunoreceptors mediates elimination of tumorigenic or virally infected cells by natural killer …

NK cells are crucial components of the innate immune system, capable of directly
eliminating infected or tumorigenic cells and regulating down-stream adaptive immune …

NKG2D is known to trigger the natural killer (NK) cell lysis of various tumor and virally
infected cells. In the NKG2D/ULBP3 complex, the structure of ULBP3 resembles the α1 and …

NKG2D, a homodimeric lectin-like receptor, is a unique stimulatory molecule that is found on
natural killer cells, T cells and activated macrophages. The natural ligands for murine …

Natural killer (NK) cells function through a diverse array of cell-surface natural killer
receptors (NCRs). NCRs specific for classical and non-classical MHC class I proteins …

The homodimeric immunoreceptor NKG2D drives the activation of effector cells following
engagement of diverse, conditionally expressed MHC class I-like protein ligands. NKG2D …

NKG2D recognizes multiple diverse ligands. Despite recent efforts in determining the crystal
structures of NKG2D-ligand complexes, the principle governing this receptor-ligand …

The natural killer gene complex (NKC) encodes several dozens of C-type lectin-like
receptors that, in various ways, tune the reactivity of NK cells and other cytotoxic …

Abstract The NKG2D-DAP10 receptor complex activates natural killer (NK) cells and
costimulates effector T cell subsets upon engagement of ligands that can be conditionally …

The recognition of human leukocyte antigen (HLA)-E by the heterodimeric CD94-NKG2
natural killer (NK) receptor family is a central innate mechanism by which NK cells monitor …