Lysophosphatidic acid, ceramide 1-phosphate and sphingosine 1-phosphate in peripheral blood of patients with idiopathic pulmonary fibrosis
T Tanaka, K Koyama, N Takahashi, K Morito… - The Journal of Medical …, 2022 - jstage.jst.go.jp
Idiopathic pulmonary fibrosis (IPF) is the most common idiopathic interstitial pneumonias.
Lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) are signaling lipids that …
Lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) are signaling lipids that …
Role of the lysophospholipid mediators lysophosphatidic acid and sphingosine 1-phosphate in lung fibrosis
BS Shea, AM Tager - Proceedings of the American Thoracic Society, 2012 - atsjournals.org
Aberrant wound healing responses to lung injury are believed to contribute to fibrotic lung
diseases, such as idiopathic pulmonary fibrosis (IPF). The lysophospholipids …
diseases, such as idiopathic pulmonary fibrosis (IPF). The lysophospholipids …
Sphingolipids in pulmonary fibrosis
LS Huang, V Natarajan - Advances in biological regulation, 2015 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by alveolar
epithelial cell injury, accumulation of fibroblasts/myofibroblasts and deposition of …
epithelial cell injury, accumulation of fibroblasts/myofibroblasts and deposition of …
[HTML][HTML] Serum S1P level in interstitial lung disease (ILD) is a potential biomarker reflecting the severity of pulmonary function
F Ding, Z Wang, J Wang, Y Ma, J Jin - BMC Pulmonary Medicine, 2024 - Springer
Abstract Background sphingosine-1-phosphate (S1P), a naturally occurring sphingolipid,
has been involved in pulmonary interstitial remodeling signaling. However, no study has …
has been involved in pulmonary interstitial remodeling signaling. However, no study has …
Cellular and molecular control of lipid metabolism in idiopathic pulmonary fibrosis: clinical application of the lysophosphatidic acid pathway
Y Nakamura, Y Shimizu - Cells, 2023 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a representative disease that causes fibrosis of the
lungs. Its pathogenesis is thought to be characterized by sustained injury to alveolar …
lungs. Its pathogenesis is thought to be characterized by sustained injury to alveolar …
Bioactive lipid lysophosphatidic acid species are associated with disease progression in idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive disease with significant mortality.
Prognostic biomarkers to identify rapid progressors are urgently needed to improve patient …
Prognostic biomarkers to identify rapid progressors are urgently needed to improve patient …
Docosatetraenoyl LPA is elevated in exhaled breath condensate in idiopathic pulmonary fibrosis
SB Montesi, SK Mathai, LN Brenner… - BMC Pulmonary …, 2014 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal disease with no
effective medical therapies. Recent research has focused on identifying the biological …
effective medical therapies. Recent research has focused on identifying the biological …
Sphingosine-1-phosphate is increased in patients with idiopathic pulmonary fibrosis and mediates epithelial to mesenchymal transition
J Milara, R Navarro, G Juan, T Peiró, A Serrano… - Thorax, 2012 - thorax.bmj.com
Background Idiopathic pulmonary fibrosis (IPF) is characterised by the aberrant epithelial to
mesenchymal transition (EMT) and myofibroblast accumulation. Sphingosine-1-phosphate …
mesenchymal transition (EMT) and myofibroblast accumulation. Sphingosine-1-phosphate …
Sphingosine-1-phosphate metabolism: can its enigmatic lyase promote the autophagy of fibrosis?
Idiopathic pulmonary fibrosis (IPF) is a devastating disease with a poorly understood
pathogenesis and a rising incidence. 1 Recently, an important role for bioactive lipids such …
pathogenesis and a rising incidence. 1 Recently, an important role for bioactive lipids such …
Serum metabolic profiling identified a distinct metabolic signature in patients with idiopathic pulmonary fibrosis–a potential biomarker role for LysoPC
B Rindlisbacher, C Schmid, T Geiser, C Bovet… - Respiratory …, 2018 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease of unknown etiology.
Patients present loss of lung function, dyspnea and dry cough. Diagnosis requires …
Patients present loss of lung function, dyspnea and dry cough. Diagnosis requires …