Mitophagy is the cellular process to selectively eliminate dysfunctional mitochondria,
governing the number and quality of mitochondria. Dysregulation of mitophagy may lead to …

Abstract" To be, or not to be?" This question is not only Hamlet's agony but also the dilemma
of mitochondria in a cancer cell. Cancer cells have a high glycolysis rate even in the …

The Warburg effect in tumor cells involves the uptake of high levels of glucose, enhanced
glycolysis, and the metabolism of pyruvate to lactic acid rather than oxidative phos …

Cancer cells preferentially utilize glycolysis, instead of oxidative phosphorylation, for
metabolism even in the presence of oxygen. This phenomenon of aerobic glycolysis …

Aerobic glycolysis is one of the emerging hallmarks of cancer cells. In this study, we
investigated the relationship between blocking mitochondrial pyruvate carrier (MPC) with …

During tumor development, malignant cells rewire their metabolism to meet the biosynthetic
needs required to increase their biomass and to overcome their microenvironment …

The term Mitophagy has been newly concerned in reforming the metabolic landscape inside
cancerous cells in addition to the interface between malignant cells as well as other major …

Cancer cells are different from normal cells in their metabolic properties. Normal cells mostly
rely on mitochondrial oxidative phosphorylation to produce energy. In contrast, cancer cells …

Although Warburg's discovery of intensive glucose uptake by tumors, followed by lactate
fermentation in oxygen presence of oxygen was made a century ago, it is still an area of …