Glucagon-like peptide-1 (GLP-1) and protective effects in cardiovascular disease: a new therapeutic approach for myocardial protection
TC Zhao - Cardiovascular diabetology, 2013 - Springer
Abstract Glucagon-like peptide-1 (GLP-1) is a member of the proglucagon incretin family
implicated in the control of appetite and satiety. GLP-1 has insulinotropic, insulinomimetic …
implicated in the control of appetite and satiety. GLP-1 has insulinotropic, insulinomimetic …
GLP-1 agonist-based therapies: an emerging new class of antidiabetic drug with potential cardioprotective effects
M Sulistio, C Carothers, M Mangat, M Lujan… - Current atherosclerosis …, 2009 - Springer
Cardiovascular disease is a leading cause of death in the United States and across the
world, and better therapies are constantly being sought to improve patient outcomes. Recent …
world, and better therapies are constantly being sought to improve patient outcomes. Recent …
The effect of glucagon-like peptide 1 on cardiovascular risk
J Sivertsen, J Rosenmeier, JJ Holst… - Nature Reviews …, 2012 - nature.com
Abstract Glucagon-like peptide 1 (GLP-1) is an incretin hormone responsible for
amplification of insulin secretion when nutrients are given orally, as opposed to …
amplification of insulin secretion when nutrients are given orally, as opposed to …
Glucagon-like peptide-1 and its cardiovascular effects
Recently, the crucial role of GLP-1 in cardiovascular disease has been suggested by both
preclinical and clinical studies. In vivo and in vitro studies have demonstrated cardio …
preclinical and clinical studies. In vivo and in vitro studies have demonstrated cardio …
Glucagon-like peptide 1 and the cardiovascular system
S Fava - Current Diabetes Reviews, 2014 - ingentaconnect.com
Glucagon-like peptide 1 (GLP1) is a major incretin hormone. This means that it is secreted
by the gut in response to food and helps in reducing post-prandial glucose exertion. It …
by the gut in response to food and helps in reducing post-prandial glucose exertion. It …
Potential cardioprotective action of GLP-1: from bench to bedside
KN Aronis, MA Tsoukas… - Metabolism-Clinical …, 2014 - metabolismjournal.com
Type 2 diabetes mellitus (T2DM) is a highly prevalent disease that is associated with
development of atherosclerosis and an increase in all-cause mortality. Treatment options for …
development of atherosclerosis and an increase in all-cause mortality. Treatment options for …
Emerging cardiovascular actions of the incretin hormone glucagon‐like peptide‐1: potential therapeutic benefits beyond glycaemic control?
DJ Grieve, RS Cassidy… - British journal of …, 2009 - Wiley Online Library
Glucagon‐like peptide‐1 (GLP‐1) is an incretin hormone secreted by the small intestine in
response to nutrient ingestion. It has wide‐ranging effects on glucose metabolism, including …
response to nutrient ingestion. It has wide‐ranging effects on glucose metabolism, including …
Effects of glucagon-like peptide-1 and long-acting analogues on cardiovascular and metabolic function
C Saraceni, TL Broderick - Drugs in R & D, 2007 - Springer
Although the insulinotropic role of glucagon-like peptide-1 (GLP-1) in type 2 diabetes
mellitus has been substantiated, its role in cardioprotection remains largely unknown. To …
mellitus has been substantiated, its role in cardioprotection remains largely unknown. To …
Cardiovascular and hemodynamic effects of glucagon-like peptide-1
Abstract Glucagon-like peptide-1 (GLP-1) is an incretin hormone that has been shown to
have hemodynamic and cardioprotective capacity in addition to its better characterized …
have hemodynamic and cardioprotective capacity in addition to its better characterized …
Glucagon-like peptide-1: a promising agent for cardioprotection during myocardial ischemia
Summary Glucagon-like peptide-1-(7-36) amide (GLP-1) is a human incretin hormone
responsible for the release of insulin in response to food. Pre-clinical and human …
responsible for the release of insulin in response to food. Pre-clinical and human …