Cancer-associated fibroblasts (CAFs) interact closely with cancer cells, supporting their
growth and invasion. To investigate the role of microRNA-21 (miR-21) in lung …

Background Development of efficient therapies of lung cancer and deep understanding of
their anti-tumor mechanism are very important. The aim of the present study is to investigate …

MicroRNAs (miRNAs) are small, single-stranded, non-coding RNA molecules that are
dysregulated in many types of human cancers, although their precise functions in driving …

Abstract Let-7 microRNAs (miRNAs) are highly conserved well-established promoters of
terminal differentiation that are expressed in healthy adult tissues and frequently repressed …

Circulating micro‐RNA (miR) profiles have been proposed as promising diagnostic and
prognostic biomarkers for cancer, including lung cancer. We have developed methods to …

Lung cancer is a leading cause of cancer death, and late diagnosis is one of the most
important reasons for the high mortality rate. microRNAs (miRNAs) are key players in gene …

Recent evidence shows that microRNAs (miRNAs) contribute to the biological effects of Toll-
like receptor (TLR) signaling on various cells. Our previous data showed that TLR9 signaling …

The inflammation-associated cytokine interleukin-6 (IL-6) can contribute to tumor growth and
resistance to therapy by the activation of survival mechanisms. In several human cancers, IL …

MicroRNAs (miRNAs) are a class of naturally occurring small non-coding RNAs that target
protein-coding mRNAs at the post-transcriptional level. Our previous studies suggest that mir …

Abnormal expression of let-7a microRNA (miRNA) in non-small cell lung cancer (NSCLC)
cells and tissue has been previously reported. Our objective was to investigate whether let …