Hereditary prostate cancer, a newly described variant of prostate cancer, is distinguished by
early age at onset and autosomal dominant inheritance within families. 1 We review the …

Purpose: We review the current epidemiological and genetic knowledge regarding
hereditary prostate cancer, and outline its clinical implications. Materials and Methods …

PURPOSE: Hereditary prostate cancer accounts for 5% to 10% of all prostate cancer cases.
We assessed clinical characteristics and survival in patients with hereditary prostate cancer …

The aim of this study was to characterize the pathological features of hereditary prostate
cancer, a recently recognized variant of prostate cancer with an autosomal dominant …

Purpose: We determined whether the clinical and pathological features of hereditary
prostate cancer differ from those of sporadic prostate cancer. Materials and Methods: We …

Background: It is estimated that there will be more than 244 000 new prostate cancer cases
diagnosed and that more than 40 000 men will die of this disease during 1995. Evidence …

Purpose: We answer the question of whether, following radical prostatectomy, prostate
cancer in patients with a family history of prostate cancer relapses biochemically at the same …

BACKGROUND Although all men age> 50 years are at an increased risk for the
development of prostate carcinoma, 2 major factors increase this risk: family history and …

Previous studies have demonstrated familial clustering of prostate cancer. To define the
nature of this familial aggregation and to assess whether Mendelian inheritance can explain …

This presentation reviews data on the familial component of prostate cancer and evidence to
support a role of genetic susceptibility in this common and complex disease. Data from case …