PURPOSE: The potential use of stem cells for acute and chronic renal injury is under
intensive investigation. We summarized the current literature on the potential therapeutic …

Background: Although renal tubular epithelium has a great capacity for repair it has been
suggested that the administration of mesenchymal stem cells may accelerate the recovery …

A current explanation for development of chronic renal injury is the imbalance between
injurious mechanism and regenerative repair. The possibility that stem cells contribute to the …

Hundreds of clinical trials are currently investigating the potential for mesenchymal stem
cells (MSC) to treat human disease, including kidney disease. There is tremendous …

Adult stem cells have been characterized in several tissues as a subpopulation of cells able
to maintain, generate, and replace terminally differentiated cells in response to physiological …

The potential role of stem cells in the repair of glomerular and tubular injury is under
intensive investigation. Several studies have addressed the role of endogenous bone …

The potential role of mesenchymal stem cells (MSCs, also called mesenchymal stromal
cells) in endogenous repair and cell-based therapies for acute kidney injury (AKI) is under …

The most commonly used therapeutic targets in nephrology are the reduction of injury, the
delay of progression, or renal replacement therapy. Many animal and human studies …

The kidney has a remarkable capacity to regenerate after injury, as it is not a terminally
differentiated organ. This regenerative potential is somehow incomplete, however, and as …

Mesenchymal stem cells are a heterogeneous population of fibroblast‐like stromal cells that
have been isolated from the bone marrow and a number of organs and tissues including the …