Backgrounds Despite the potential therapeutic benefits, cell therapy in renal ischemia-
reperfusion (I/R) injury is currently limited by low rates of cell engraftment after systemic …

New and effective treatment for acute kidney injury remains a challenge. Here, we induced
mouse hematopoietic stem and progenitor cells (HSPC) to differentiate into cells that …

Mesenchymal stem cell interactions with growth factors on ki... : Current Opinion in Nephrology
and Hypertension Mesenchymal stem cell interactions with growth factors on kidney repair …

Background: Ischaemia-reperfusion injury (IRI) remains one of the leading causes of acute
kidney injury (AKI). IRI is an underlying multifactorial pathophysiological process which …

Endothelial progenitor cells (EPC) and mesenchymal stem cells (MSC) augment tissue
repair but possess slightly different properties. How the cellular phenotype affects the …

The mechanism of mesenchymal stem cell therapy in acute kidney injury remains uncertain.
Previous studies indicated that mesenchymal stem cells could attenuate inflammation …

Acute kidney injury (AKI) is a major clinical problem in which a critical vascular,
pathophysiological component is recognized. We demonstrated previously that …

Kidney tubular epithelium is restored without replacement with bone marrow-derived cells
during repair after ischemic injury. The kidney has the ability to restore the structural and …

Bone marrow-derived mesenchymal stem cells (MSCs) have the capacity to regenerate
renal tubule epithelia and repair renal function without fusing with resident tubular cells. The …

Acute renal failure (ARF) seriously worsens prognosis of hospitalized patients. The
dysfunction and apoptosis/necrosis of tubular epithelial cells is of key importance for the …