Axon regeneration in C. elegans
M Hammarlund, Y Jin - Current Opinion in Neurobiology, 2014 - Elsevier
Highlights•Genetic screening reveals relevant molecules and expands molecular landscape
of axon regeneration.•In-depth mechanistic dissection uncovers signaling pathways.•In vivo …
of axon regeneration.•In-depth mechanistic dissection uncovers signaling pathways.•In vivo …
Axon regeneration mechanisms: insights from C. elegans
L Chen, AD Chisholm - Trends in cell biology, 2011 - cell.com
Understanding the mechanisms of axon regeneration is of great importance to the
development of therapeutic treatments for spinal cord injury or stroke. Axon regeneration …
development of therapeutic treatments for spinal cord injury or stroke. Axon regeneration …
Neural Regeneration in Caenorhabditis elegans
RE Bejjani, M Hammarlund - Annual review of genetics, 2012 - annualreviews.org
Axon regeneration is a medically relevant process that can repair damaged neurons. This
review describes current progress in understanding axon regeneration in the model …
review describes current progress in understanding axon regeneration in the model …
Caenorhabditis elegans: A new model organism for studies of axon regeneration
A Ghosh‐Roy, AD Chisholm - Developmental dynamics: an …, 2010 - Wiley Online Library
Axonal regeneration in Caenorhabditis elegans was first reported five years ago. Individual
green fluorescent protein‐labeled axons can be severed using laser microsurgery and their …
green fluorescent protein‐labeled axons can be severed using laser microsurgery and their …
Axon regeneration in C. elegans: worming our way to mechanisms of axon regeneration
AB Byrne, M Hammarlund - Experimental neurology, 2017 - Elsevier
How axons repair themselves after injury is a fundamental question in neurobiology. With its
conserved genome, relatively simple nervous system, and transparent body, C. elegans has …
conserved genome, relatively simple nervous system, and transparent body, C. elegans has …
[HTML][HTML] Signal transduction cascades in axon regeneration: insights from C. elegans
N Hisamoto, K Matsumoto - Current Opinion in Genetics & Development, 2017 - Elsevier
Highlights•The nematode Caenorhabditis elegans has recently emerged as a genetic model
for studying regenerative responses in neurons.•Axon regeneration is regulated by a …
for studying regenerative responses in neurons.•Axon regeneration is regulated by a …
Genetic dissection of axon regeneration
Z Wang, Y Jin - Current opinion in neurobiology, 2011 - Elsevier
Axon regeneration has long been studied in vertebrate model organisms and neuronal
cultures. Recent development of axon regeneration paradigms in genetic model organisms …
cultures. Recent development of axon regeneration paradigms in genetic model organisms …
The Genetics of Axon Guidance and Axon Regeneration in Caenorhabditis elegans
The correct wiring of neuronal circuits depends on outgrowth and guidance of neuronal
processes during development. In the past two decades, great progress has been made in …
processes during development. In the past two decades, great progress has been made in …
[HTML][HTML] Axon regeneration pathways identified by systematic genetic screening in C. elegans
L Chen, Z Wang, A Ghosh-Roy, T Hubert, D Yan… - Neuron, 2011 - cell.com
The mechanisms underlying the ability of axons to regrow after injury remain poorly
explored at the molecular genetic level. We used a laser injury model in Caenorhabditis …
explored at the molecular genetic level. We used a laser injury model in Caenorhabditis …
Distinct cellular and molecular mechanisms mediate initial axon development and adult-stage axon regeneration in C. elegans
The molecular and cellular mechanisms that allow adult-stage neurons to regenerate
following damage are poorly understood. Recently, axons of motoneurons and …
following damage are poorly understood. Recently, axons of motoneurons and …