Comprehensive immunological analyses of colorectal cancer patients in the phase I/II study of quickly matured dendritic cell vaccine pulsed with carcinoembryonic …

M Sakakibara, T Kanto, M Hayakawa, S Kuroda… - Cancer Immunology …, 2011 - Springer
Dendritic cell (DC) vaccine has been used to treat patients with advanced colorectal cancer
(CRC). The results of vaccine-induced clinical responses have not always been satisfactory …

Generation of carcinoembryonic antigen (CEA)-specific T-cell responses in HLA-A* 0201 and HLA-A* 2402 late-stage colorectal cancer patients after vaccination with …

KJ Liu, CC Wang, LT Chen, AL Cheng, DT Lin… - Clinical cancer …, 2004 - AACR
Purpose: We intranodally immunized metastatic colorectal carcinoma patients, who had
failed standard chemotherapy, with dendritic cells (DCs) pulsed with HLA-A* 0201-or HLA …

[HTML][HTML] A phase I clinical study of immunotherapy for advanced colorectal cancers using carcinoembryonic antigen-pulsed dendritic cells mixed with tetanus toxoid …

KJ Liu, TY Chao, JY Chang, AL Cheng… - Journal of biomedical …, 2016 - Springer
Background To better evaluate and improve the efficacy of dendritic cell (DC)-based cancer
immunotherapy, we conducted a clinical study of patients with advanced colorectal cancer …

Vaccination of metastatic colorectal cancer patients with matured dendritic cells loaded with multiple major histocompatibility complex class I peptides

B Kavanagh, A Ko, A Venook, K Margolin… - Journal of …, 2007 - journals.lww.com
Developing a process to generate dendritic cells (DCs) applicable for multicenter trials
would facilitate cancer vaccine development. Moreover, targeting multiple antigens with …

[HTML][HTML] Vaccination of colorectal cancer patients with CEA-loaded dendritic cells: antigen-specific T cell responses in DTH skin tests

WJ Lesterhuis, IJM De Vries, DH Schuurhuis… - Annals of …, 2006 - Elsevier
Abstract Background Dendritic cells (DCs) are the professional antigen-presenting cells of
the immune system. As such they are currently used in clinical vaccination protocols in …

Clinical responses in patients with advanced colorectal cancer to a dendritic cell based vaccine

SK Burgdorf, A Fischer, PS Myschetzky… - Oncology …, 2008 - spandidos-publications.com
Patients with disseminated colorectal cancer have a poor prognosis. Preliminary studies
have shown encouraging results from vaccines based on dendritic cells. The aim of this …

Induction of tumor-specific T-cell responses by vaccination with tumor lysate-loaded dendritic cells in colorectal cancer patients with carcinoembryonic-antigen positive …

A Tamir, E Basagila, A Kagahzian, L Jiao… - Cancer Immunology …, 2007 - Springer
Abstract Background Dendritic cells (DCs) are the most effective antigen-presenting cells. In
the last decade, the use of DCs for immunotherapy of cancer patients has been vastly …

Immunogenicity of dendritic cells pulsed with CEA peptide or transfected with CEA mRNA for vaccination of colorectal cancer patients

WJ Lesterhuis, IJM De Vries, G Schreibelt… - Anticancer …, 2010 - ar.iiarjournals.org
Background: Dendritic cells (DCs) are the professional antigen-presenting cells of the
immune system. We have demonstrated that vaccination of autologous ex vivo cultured DCs …

Long-term vaccine therapy with autologous whole tumor cell-pulsed dendritic cells for a patient with recurrent rectal carcinoma

H Onishi, T Morisaki, E Baba, M Nakamura… - Anticancer …, 2011 - ar.iiarjournals.org
We performed continuous dendritic cells (DCs) vaccination to treat a patient with
chemotherapy-resistant recurrent rectal carcinoma and lung and bone metastases. A patient …

Induction of cellular immune responses against carcinoembryonic antigen in patients with metastatic tumors after vaccination with altered peptide ligand-loaded …

J Babatz, C Röllig, B Löbel, G Folprecht… - Cancer Immunology …, 2006 - Springer
Abstract Purpose: Dendritic cells (DCs) are characterized by their extraordinary capacity to
induce T-cell responses, providing the opportunity of DC-based cancer vaccination …