Differential Gene Expression Profiles of PPP2R5C-siRNA-Treated Malignant T Cells

Y Chen, S Liu, Q Shen, X Zha, H Zheng… - DNA and Cell …, 2013 - liebertpub.com
Recently, alterations in the expression pattern of PPP2R5C associated with malignant
transformation have been characterized, and PPP2R5C overexpression was demonstrated …

[HTML][HTML] Expression and distribution of PPP2R5C gene in leukemia

H Zheng, Y Chen, S Chen, Y Niu, L Yang, B Li… - Journal of hematology & …, 2011 - Springer
Background Recently, we clarified at the molecular level novel chromosomal translocation t
(14; 14)(q11; q32) in a case of Sézary syndrome, which caused a rearrangement from …

[HTML][HTML] Alteration of gene expression profile following PPP2R5C knockdown may be associated with proliferation suppression and increased apoptosis of K562 cells

S Liu, Q Shen, Y Chen, C Zeng, C Cao, L Yang… - Journal of Hematology & …, 2015 - Springer
We reported that knockdown of PPP2R5C by siRNA led to proliferation inhibition and
apoptosis induction in K562 cells. In this study, we further characterized the gene expression …

Knockdown of PPP5C inhibits growth of hepatocellular carcinoma cells in vitro

L Feng, P Sun, Z Li, M Liu, S Sun - Applied biochemistry and …, 2015 - Springer
Ser/Thr protein phosphatase 5 (PPP5C) has been reported to participate in tumor
progression. However, its functional role in hepatocellular carcinoma (HCC) remains …

[HTML][HTML] PPP1R14B is a prognostic and immunological biomarker in pan-cancer

M Deng, L Peng, J Li, X Liu, X Xia, G Li - Frontiers in genetics, 2021 - frontiersin.org
Recent studies have shown that PPP1R14B was highly expressed in tumor tissues and
patients with high expression of PPP1R14B had poor survival rates. However, the function …

Plasmid-based STAT3-siRNA efficiently inhibits breast tumor growth and metastasis in mice.

L Dai, L Cheng, X Zhang, Q Jiang, S Zhang, S Wang… - Neoplasma, 2011 - europepmc.org
Signal transducer and activator of transcription 3 (STAT3) plays an important role in the
tumor formation and metastasis. In this study, short hairpin RNA targeting STAT3 was cloned …

Knockdown of protein phosphatase 5 (PPP5C) suppresses the growth of leukemic cell line U937

GY Li, JZ Liu, L Zhang, SJ Li, GZ Liu… - Cellular and Molecular …, 2016 - cellmolbiol.org
Serine/threonine protein phosphatase 5 (PPP5C) participates in multiple signaling pathways
including cell cycle control and cell growth. PPP5C is involved in the progression of human …

RETRACTED: Overexpression of miR-222-3p Promotes the Proliferation and Inhibits the Apoptosis of Diffuse Large B-Cell Lymphoma Cells via Suppressing …

S Sun, H Wang, M Ji - Technology in cancer research & …, 2019 - journals.sagepub.com
Purpose: This study aimed to investigate the effects of microRNA-222-3p on activated B cell-
like-type diffuse large B-cell lymphoma cells and the regulatory relationship between …

[HTML][HTML] PTPN22 silencing in human acute T-cell leukemia cell line (Jurkat cell) and its effect on the expression of miR-181a and miR-181b

E Baghbani, V Khaze, S Sadreddini… - Advanced …, 2018 - ncbi.nlm.nih.gov
Purpose: T-cell acute lymphoblastic leukemia (T-ALL) is one of the most common
malignancies associated with T-lymphocytes, accounting for 10 to 15 percent of ALL cases …

[HTML][HTML] Suppression of STAT5A and STAT5B chronic myeloid leukemia cells via siRNA and antisense-oligonucleotide applications with the induction of apoptosis

BT Kaymaz, N Selvi, AA Gokbulut, Ç Aktan… - American journal of …, 2013 - ncbi.nlm.nih.gov
Signal transducers and activators of transcription (STAT) proteins function in the JAK/STAT
signaling pathway and are activated by phosphorylation. As a result of this signaling event …