Objectives: Controversy remains over the impact of dental adhesives on gelatinolytic activity
in dentin. In this study, we aimed to confirm or reject the existence of a definitive cause/effect …

Adhesive procedures activate dentin-associated matrix metalloproteinases (MMPs), and so
iatrogenically initiate bond degradation. We hypothesized that adding MMP inhibitors to …

Purpose: To examine the effect of grape seed extract (GSE) pretreatment on the reduction of
active gelatinases when using universal adhesives in etch-and-rinse mode. Materials and …

The vulnerability of the bonding interface occurs because of the degradation of hybrid layer
due to the presence of water and proteolytic enzymes, which interferes on the longevity of …

De Munck J, Mine A, Van den Steen PE, Van Landuyt KL, Poitevin A, Opdenakker G, Van
Meerbeek B. Enzymatic degradation of adhesive–dentin interfaces produced by mild self …

Mild acids are known to activate dentin matrix metalloproteinase (MMPs). All self‐etching
dental adhesives are acidic (pH 1.5–2.7) and may activate dentin MMPs. The purpose of this …

This study evaluated epigallocatechin-3-gallate (EGCG) and epigallocatechin-3-O-(3-O-
methyl)-gallate (EGCG-3Me) modified etch-and-rinse adhesives (Single Bond 2, SB 2) for …

(1) Background: The objective of this in vitro study was to evaluate the impact of different
etching times and ethanol pre-treatments on the immediate bond strength of a hydrophilic …

Objective To investigate the effect of collagen cross-links on the stability of adhesive
properties, the degree of conversion within the hybrid layer, cytotoxicity and the inhibition …

Endogeneous proteolytic responses in dentin bonding interface have addressing to
strategies to preventive and therapeutic approaches of clinical use of dentin bonding …