Adipose tissue macrophages: the inflammatory link between obesity and cancer?
M Wagner, ES Samdal Steinskog… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Obesity has increased dramatically over the last three decades. Thus,
epidemiological evidence linking obesity and cancer has ignited our interest in the …
epidemiological evidence linking obesity and cancer has ignited our interest in the …
[HTML][HTML] The adipocyte–macrophage relationship in cancer: A potential target for antioxidant therapy
Obesity has emerged as a major public health concern with a staggering 39% worldwide
prevalence as of 2021. Given the magnitude of the problem and considering its association …
prevalence as of 2021. Given the magnitude of the problem and considering its association …
Obesity programs macrophages to support cancer progression
Obesity induces multifactorial effects such as dyslipidemia, insulin resistance, and arterial
hypertension that influence the progression of many diseases. Obesity is associated with an …
hypertension that influence the progression of many diseases. Obesity is associated with an …
[HTML][HTML] The impact of obesity, adipose tissue, and tumor microenvironment on macrophage polarization and metastasis
O Habanjar, M Diab-Assaf, F Caldefie-Chezet, L Delort - Biology, 2022 - mdpi.com
Simple Summary The inflammatory adipose microenvironment in obesity plays a crucial role
in cancer development and metastases. By focusing on adipocytes and macrophages, as …
in cancer development and metastases. By focusing on adipocytes and macrophages, as …
[HTML][HTML] Obesity and cancer: the role of adipose tissue and adipo-cytokines-induced chronic inflammation
Adipose tissue in addition to its ability to keep lipids is now recognized as a real organ with
both metabolic and endocrine functions. Recent studies demonstrated that in obese animals …
both metabolic and endocrine functions. Recent studies demonstrated that in obese animals …
Adipocytes: impact on tumor growth and potential sites for therapeutic intervention
S Hefetz-Sela, PE Scherer - Pharmacology & therapeutics, 2013 - Elsevier
The prevalence of obesity has increased dramatically in recent decades, reaching epidemic
proportions. It is becoming clear that obesity is associated not only with type 2 diabetes …
proportions. It is becoming clear that obesity is associated not only with type 2 diabetes …
[HTML][HTML] Human adipose tissue macrophages display activation of cancer-related pathways
TH Mayi, M Daoudi, B Derudas, B Gross… - Journal of Biological …, 2012 - ASBMB
Obesity is associated with a significantly increased risk for cancer suggesting that adipose
tissue dysfunctions might play a crucial role therein. Macrophages play important roles in …
tissue dysfunctions might play a crucial role therein. Macrophages play important roles in …
Cytokines, obesity, and cancer: new insights on mechanisms linking obesity to cancer risk and progression
CA Gilbert, JM Slingerland - Annual review of medicine, 2013 - annualreviews.org
Obesity is a problem of epidemic proportions in many developed nations. Increased body
mass index and obesity are associated with a significantly worse outcome for many cancers …
mass index and obesity are associated with a significantly worse outcome for many cancers …
The role of immune dysfunction in obesity-associated cancer risk, progression, and metastasis
A Kulkarni, LW Bowers - Cellular and Molecular Life Sciences, 2021 - Springer
Obesity has been linked to an increased risk of and a worse prognosis for several types of
cancer. A number of interrelated mediators contribute to obesity's pro-tumor effects …
cancer. A number of interrelated mediators contribute to obesity's pro-tumor effects …
[HTML][HTML] Adipose tissue immunity and cancer
Inflammation and altered immune response are important components of obesity and
contribute greatly to the promotion of obesity-related metabolic complications, especially …
contribute greatly to the promotion of obesity-related metabolic complications, especially …
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