Macrophage-targeted therapeutics for metabolic disease
Macrophages are cells of the innate immune system that are resident in all tissues, including
metabolic organs such as the liver and adipose tissue (AT). Because of their phenotypic …
metabolic organs such as the liver and adipose tissue (AT). Because of their phenotypic …
Local delivery strategies to restore immune homeostasis in the context of inflammation
ER Bentley, SR Little - Advanced drug delivery reviews, 2021 - Elsevier
Immune homeostasis is maintained by a precise balance between effector immune cells and
regulatory immune cells. Chronic deviations from immune homeostasis, driven by a greater …
regulatory immune cells. Chronic deviations from immune homeostasis, driven by a greater …
Delivery strategies to control inflammatory response: Modulating M1–M2 polarization in tissue engineering applications
Macrophages are key players in many physiological scenarios including tissue
homeostasis. In response to injury, typically the balance between macrophage sub …
homeostasis. In response to injury, typically the balance between macrophage sub …
Drug delivery strategies to control macrophages for tissue repair and regeneration
R Garash, A Bajpai… - Experimental biology …, 2016 - journals.sagepub.com
Tissue repair and regeneration is a complex process. Our bodies have an excellent capacity
to regenerate damaged tissues in many situations. However, tissue healing is impaired in …
to regenerate damaged tissues in many situations. However, tissue healing is impaired in …
Local drug delivery systems for inflammatory diseases: Status quo, challenges, and opportunities
Inflammation that is not resolved in due course becomes a chronic disease. The treatment of
chronic inflammatory diseases involves a long-term use of anti-inflammatory drugs such as …
chronic inflammatory diseases involves a long-term use of anti-inflammatory drugs such as …
An overview on macrophage targeting: a promising approach
VD Vemuri, R Kushwaha, G Gowri… - Critical Reviews™ in …, 2023 - dl.begellhouse.com
Macrophages are immuno cells with high flexibility among hematopoietic system.
Macrophages are tangled with many diseases like chronic inflammatory, atherosclerosis …
Macrophages are tangled with many diseases like chronic inflammatory, atherosclerosis …
Macrophage-associated disorders: pathophysiology, treatment challenges, and possible solutions
K Yadav, M Pradhan, D Singh, MR Singh - Macrophage Targeted Delivery …, 2022 - Springer
Immune disorders are a self-attacking state of our defense mechanism influencing diverse
body tissues and organs. One of the most significant obstacles in treatment for immune …
body tissues and organs. One of the most significant obstacles in treatment for immune …
Advancements in macrophage-targeted drug delivery for effective disease management
H Liu, H Lv, X Duan, Y Du, Y Tang… - International Journal of …, 2023 - Taylor & Francis
Macrophages play a crucial role in tissue homeostasis and the innate immune system. They
perform essential functions such as presenting antigens, regulating cytokines, and …
perform essential functions such as presenting antigens, regulating cytokines, and …
Multi-compartmental nanoparticles-in-emulsion formulation for macrophage-specific anti-inflammatory gene delivery
H Attarwala, M Amiji - Pharmaceutical research, 2012 - Springer
Purpose To develop a safe and effective non-viral vector for gene delivery and transfection
in macrophages for potential anti-inflammatory therapy. Methods Solid nanoparticles-in …
in macrophages for potential anti-inflammatory therapy. Methods Solid nanoparticles-in …
Targeting monocyte and macrophage subpopulations for immunotherapy: a patent review (2009–2013)
WD Jackson, KJ Woollard - Expert Opinion on Therapeutic Patents, 2014 - Taylor & Francis
Introduction: Monocytes and macrophages are heterogeneous populations of effector cells
in the innate immune system. Once thought to be obligatory precursors for macrophages …
in the innate immune system. Once thought to be obligatory precursors for macrophages …