Macrophages have been extensively used in the development of drug delivery systems, as
they can prolong the circulation and release of drugs, extend their half-life, increase their …

Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous
system. It is characterized by demyelination of neurons and loss of neuronal axons and …

Advances in the field of tissue engineering have enhanced the potential of regenerative
medicine, yet the efficacy of these strategies remains incomplete, and is limited by the innate …

Particulate systems in the form of liposomes, polymeric micelles, polymeric nano-and
microparticles, and many others offer a rational approach for selective delivery of therapeutic …

Introduction Macrophages are involved in the normal defense of the body; however, the
varying phenotypes of macrophages and imbalance in their ratio lead to the impairment of …

As the role of monocytes and macrophages in a range of diseases is better understood,
strategies to target these cell types are of growing importance both scientifically and …

The immune system is one of the most important, complex biological networks regulating
and protecting human health. Its precise modulation can prevent deadly infections and fight …

Macrophages are key modulators of all inflammatory diseases and essential for their
resolution, making macrophage cell therapy a promising strategy for regenerative medicine …

The beginning of the 21st century saw numerous protein and peptide therapeuticals both on
the market and entering the final stages of clinical studies. They represent a new category of …

Inflammatory processes are increasingly being identified at the core of many different
disease states (eg heart disease, cancer, diabetes). As such, anti-inflammatory strategies …