Temperature is a critical environmental signal, which exerts powerful control over the
development and virulence of diverse microbial pathogens. Fungi, along with other …

Temperature change is a ubiquitous environmental signal, which exerts powerful control
over the development and virulence of microbial pathogens. For Candida albicans, the …

Hsp90 is environmentally contingent molecular chaperone that influences the form and
function of diverse signal transducers. Here we discuss our recent findings that Hsp90 …

Background Temperature exerts powerful control over development and virulence of diverse
pathogens. In the leading human fungal pathogen, Candida albicans, temperature governs …

Background Hsp90 is an environmentally contingent molecular chaperone that influences
the form and function of diverse regulators of cellular signaling. Hsp90 potentiates the …

The molecular chaperone Hsp90 orchestrates regulatory circuitry governing fungal
morphogenesis, biofilm development, drug resistance, and virulence. Hsp90 functions in …

Hsp90 is a conserved molecular chaperone that facilitates the folding and function of client
proteins. Hsp90 function is dynamically regulated by interactions with co-chaperones and by …

Highlights•Hsp90 is a molecular chaperone that modulates the function of many client
proteins.•Morphogenesis is an important Candida albicans virulence trait.•Hsp90 regulates …

The trimorphic fungus Candida albicans is the leading cause of systemic candidiasis, a
disease with poor prognosis affecting immunocompromised individuals. The capacity of C …

The trimorphic fungus Candida albicans is the leading cause of systemic candidiasis, a
disease with poor prognosis affecting immunocompromised patients. The capacity to switch …