[HTML][HTML] Genetic damage and potential mechanism exploration under different air pollution patterns by multi-omics

J Xu, Q Zhang, Z Su, Y Liu, T Yan, Y Zhang… - Environment …, 2022 - Elsevier
Ambient air pollution was classified as carcinogenic to humans (Group 1) for lung cancer.
DNA damage was an important first step in the process of carcinogenesis, and could also be …

DNA damage, serum metabolomic alteration and carcinogenic risk associated with low-level air pollution

J Xu, Y Liu, Q Zhang, Z Su, T Yan, S Zhou, T Wang… - Environmental …, 2022 - Elsevier
Outdoor air pollution has been classified as carcinogenic to humans (Group 1) for lung
cancer, but the underlying mechanism and key toxic components remain incompletely …

Real-world PM2.5 exposure induces pathological injury and DNA damage associated with miRNAs and DNA methylation alteration in rat lungs

L Zhao, M Zhang, L Bai, Y Zhao, Z Cai… - … Science and Pollution …, 2022 - Springer
Abstract Fine particulate matter (PM 2.5) has been demonstrated to threaten public health
and increase lung cancer risk. DNA damage is involved in the pathogenesis of lung cancer …

[HTML][HTML] Epigenetic related changes on air quality

Á Del Real, A Santurtún, MT Zarrabeitia - Environmental Research, 2021 - Elsevier
The exposure to airborne particulate matter (PM) increases the risk of developing human
diseases. Epigenetic mechanisms have been related to environmental exposures and …

Integrated mitoepigenetic signalling mechanisms associated with airborne particulate matter exposure: A cross-sectional pilot study

PK Mishra, A Bhargava, R Kumari, N Bunkar… - Atmospheric Pollution …, 2022 - Elsevier
Airborne particulate matter (PM) is known to be associated with various chronic human
ailments, however, precise underlying molecular mechanisms remains elusive. Based on …

Airborne particulate matter induces oxidative damage, DNA adduct formation and alterations in DNA repair pathways

EM Quezada-Maldonado, Y Sánchez-Pérez… - Environmental …, 2021 - Elsevier
Air pollution, which includes particulate matter (PM), is classified in group 1 as a carcinogen
to humans by the International Agency for Research in Cancer. Specifically, PM exposure …

[HTML][HTML] Assessment on the lung injury of mice posed by airborne PM2. 5 collected from developing area in China and associated molecular mechanisms by …

S Dai, Z Wang, Y Yang, T Guo, W Li - Ecotoxicology and Environmental …, 2021 - Elsevier
Some epidemiological evidences showed exposure of airborne fine particulate matter (PM
2.5) was associated with lung dysfunction. However, the adverse effects of PM 2.5 from mid …

[HTML][HTML] Predictive and prognostic biomarkers of respiratory diseases due to particulate matter exposure

HJ Kim, MG Choi, MK Park, YR Seo - Journal of cancer prevention, 2017 - ncbi.nlm.nih.gov
Air pollution is getting severe and concerns about its toxicity effects on airway and lung
disease are also increasing. Particulate matter (PM) is major component of air pollutant. It …

Particulate matter‐induced epigenetic changes and lung cancer

J Li, WX Li, C Bai, Y Song - The clinical respiratory journal, 2017 - Wiley Online Library
Abstract Background and Aims: Lung cancer is the leading cause of cancer death
worldwide. Cigarette smoking is the well‐known risk factor for lung cancer. Epidemiological …

Differences in transcriptome response to air pollution exposure between adult residents with and without chronic obstructive pulmonary disease in Beijing: A panel …

Y Yao, X Chen, W Chen, Y Han, T Xue, J Wang… - Journal of Hazardous …, 2021 - Elsevier
Ambient air pollution is a major risk factor for the prevalence and exacerbation of chronic
obstructive pulmonary disease (COPD). Based on the COPDB (COPD in Beijing) panel …