AML with translocation t (3; 5) belongs to the “AML with myelodysplasia-related changes”
defined in the 2008 WHO classification. 1 The incidence of this balanced abnormality is less …

Balanced translocations are rare in myelodysplasia (MDS) and acute myeloid leukemia
(AML) with multilineage dysplasia; however, the t (3; 5)(q25; q35) and insertion variant occur …

The classification of acute myeloid leukemia (AML) recognizes a subgroup of diseases with
recurring genetic abnormalities. Translocation (15; 17) is the marker of acute promyelocitic …

Cytogenetic abnormalities play an important role in diagnosis, classification and prognosis
in acute myeloid leukemia (AML). Nevertheless, several chromosome abnormalities have …

Translocation (3; 5) is an uncommon karyotypic aberration in acute myeloid leukemia (AML).
With the exception of M3, t (3; 5) has been reported in every other subtype of AML, being …

MLL-rearranged acute myeloid leukemia (AML) is associated with an adverse outcome in
most treatment protocols. The MLL-gene exhibits an 8-kb breakpoint cluster region, which …

Acute myeloid leukemia (AML) with the t (7; 12)(q36; p13) translocation occurs only in very
young children and has a poor clinical outcome. The expected oncofusion between …

We present a novel case of acute myeloid leukemia with an NPM1/MLF1 rearrangement in a
78-year-old Korean woman. The bone marrow chromosome study showed a complex …

Abstract Objectives: Session 1 of the 2013 Society for Hematopathology/European
Association for Hematopathology Workshop was devoted to the cases of acute myeloid …

The complex variants of t (8; 21) involving chromosomes 8 and 21 as well as a variable
chromosome account for 1.1∼ 5% of acute myeloid leukemia (AML) patients. This paper …