Hutchinson-Gilford progeria syndrome (HGPS) is a rare, debilitating disease with early
mortality and rapid onset of aging-associated pathologies. It is linked to mutations in LMNA …

Hutchinson–Gilford progeria syndrome (HGPS) is a rare genetic disorder characterized by
dramatic premature aging. Classic HGPS is caused by a de novo point mutation in exon 11 …

Hutchinson-Gilford progeria syndrome (HGPS) is a devastating premature aging disease
resulting from a mutation in the LMNA gene, which encodes nuclear lamins A and C. Lamin …

Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare premature aging disorder caused
by a de novo heterozygous point mutation G608G (GGC> GGT) within exon 11 of LMNA …

Lamin A is a component of the nuclear envelope that is synthesized as a precursor prelamin
A molecule and then processed into mature lamin A through sequential steps of …

Hutchinson-Gilford progeria syndrome (HGPS) is caused by a mutation in LMNA that
produces an aberrant lamin A protein, progerin. The accumulation of progerin in HGPS cells …

Hutchinson-Gilford progeria syndrome (HGPS) is a lethal genetic disorder characterized by
premature aging. HGPS is most commonly caused by a de novo single-nucleotide …

The Hutchinson–Gilford progeria syndrome (HGPS) is a premature aging disease caused by
mutations of the LMNA gene leading to increased production of a partially processed form of …

Hutchinson-Gilford progeria syndrome (HGPS) is a rare human genetic disease that leads to
a severe premature ageing phenotype, caused by mutations in the LMNA gene. The LMNA …

Mutations in the lamin A/C gene cause the rare genetic disorder Hutchinson–Gilford
progeria syndrome (HGPS). The prevalent mutation results in the production of a mutant …