Fibrinolysis resistance: a potential mechanism underlying COVID-19 coagulopathy

E Weiss, O Roux, JD Moyer… - Thrombosis and …, 2020 - thieme-connect.com
We read with great interest the article by Spiezia et al, published in a recent issue of the
journal, showing a severe hypercoagulability on thromboelastometry profiles of 22 critically …

COVID-19 is associated with an acquired factor XIII deficiency

FA von Meijenfeldt, S Havervall… - Thrombosis and …, 2021 - thieme-connect.com
Coronavirus disease 2019 (COVID-19) is associated with an increased risk of thrombotic
complications. 1 Multiple lines of evidence support the existence of a hypercoagulable state …

Circulating plasminogen concentration at admission in patients with coronavirus disease 2019 (COVID-19)

BM Henry, SW Benoit, J Hoehn, G Lippi… - … in thrombosis and …, 2020 - thieme-connect.com
The pathophysiology of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has puzzled the medical community …

Is it hyperfibrinolysis or fibrinolytic shutdown in severe COVID-19?

ND Nielsen, MA Rollins-Raval, JS Raval, J Thachil - Thrombosis Research, 2022 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a respiratory virus that
can cause severe illness (COVID-19) in infected individuals. Infected individuals with severe …

Studies on hemostasis in COVID‐19 deserve careful reporting of the laboratory methods, their significance, and their limitations

M Hardy, J Douxfils, M Bareille, S Lessire… - Journal of Thrombosis …, 2020 - jthjournal.org
We read with much interest the recent observational study of Nougier et al, which aimed at
studying thrombin generation (TG) and fibrinolysis profiles of coronavirus disease 2019 …

COVID-19 patient plasma demonstrates resistance to tPA-induced fibrinolysis as measured by thromboelastography

CL Maier, T Sarker, F Szlam, RM Sniecinski - Journal of Thrombosis and …, 2021 - Springer
Patients critically ill with COVID-19 are at risk for thrombotic events despite prophylactic
anticoagulation. Impaired fibrinolysis has been proposed as an underlying mechanism. Our …

More on COVID-19 coagulopathy in Caucasian patients

H Fogarty, L Townsend, C Ni Cheallaigh, C Bergin… - 2021 - repository.rcsi.com
We are grateful for the comments of Marrietta et al. 1 and welcome the opportunity to provide
further details on the coagulopathy observed in our patients with coronavirus disease 2019 …

Venous thromboembolism in COVID‐19 patients

A Porfidia, R Pola - Journal of thrombosis and haemostasis, 2020 - jthjournal.org
Dear Editor, We read with interest the study published by Tang et al1 in a recent issue of the
Journal of Thrombosis and Haemostasis. In this retrospective analysis, conducted at the …

Personalizing antithrombotic therapy in COVID-19: role of thromboelastography and thromboelastometry

R Chaudhary, RP Kreutz, KP Bliden… - Thrombosis and …, 2020 - thieme-connect.com
Coronavirus-2019 (COVID-19) infection is responsible for the pandemic outbreak across the
world. The pathophysiology of COVID-19 has been characterized by endothelial …

Potential of heparin and nafamostat combination therapy for COVID‐19

H Asakura, H Ogawa - Journal of Thrombosis and Haemostasis, 2020 - jthjournal.org
Tang et al recently reported that, in COVID-19 infections caused by the novel coronavirus
(SARS-CoV-2), heparin anticoagulant therapy lowers the mortality rate in patients who …