A growing body of evidence suggests that the risk of development and progression of a
variety of human chronic diseases depends on epigenetic modifications triggered by …

Abstract Purpose of Review There is interest in evaluating the developmental origins of
health and disease (DOHaD) which emphasizes the role of prenatal and early-life …

Epigenetics, and especially DNA methylation, have recently become provocative biological
explanations for early-life environmental effects on later health. Despite the large increase in …

Environmental epigenetics Traditional research on the combined effects of genetics and the
environment investigates how individuals differ in susceptibility to disease and how …

Evidence from both human and animal studies has shown that the prenatal and early
postnatal environments influence susceptibility to chronic disease in later life and suggests …

This review focuses on how environmental factors through epigenetics modify disease risk
and health outcomes. Major epigenetic events, such as histone modifications, DNA …

The field of Developmental Origins of Health and Disease (DOHaD) seeks to understand the
relationships between early-life environmental exposures and long-term health and disease …

Traditional studies on the combined effects of genetics and the environment on individual
variation in disease susceptibility primarily focus on single nucleotide polymorphisms that …

Abstract Changes in epigenetic marks such as DNA methylation and histone acetylation are
associated with a broad range of disease traits, including cancer, asthma, metabolic …

This review considers the emerging relationships between environmental factors and
epigenetic alterations and the application of genome-wide assessments to better define …