The G protein γ13 subunit (Gγ13) is expressed in taste and retinal and neuronal tissues and
plays a key role in taste transduction. We identified PSD95, Veli-2, and other PDZ domain …

G‐protein‐mediated signalling processes are involved in sweet and bitter taste transduction.
In particular, the G protein α‐subunit gustducin has been implicated in these processes. One …

We cloned cDNAs for two G protein α-subunits belonging to the Gαq family, each capable of
activating PLCβ, from rat tongue. One is a Gαq in the narrow sense, and the other, termed rat …

The gustatory system detects tastants and transmits signals to the brain regarding ingested
substances and nutrients. Although tastant receptors and taste signaling pathways have …

Bitter taste perception is a conserved chemical sense against the ingestion of poisonous
substances in mammals. A multigene family of G-protein-coupled receptors, T2R (so-called …

Previous studies have identified many cDNA species that encode a variety of G protein α-
subunits occurring in taste buds. These include the cDNA encoding a taste-bud-specific Gα …

The mammalian tastes of sweet, umami, and bitter are initiated by activation of G protein-
coupled receptors (GPCRs) of the T1R and T2R families on taste receptor cells. GPCRs …

Gustducin, a Gα subunit expressed in taste cells, is known as a key molecule for sweet,
umami and bitter taste signal transduction. However, previous studies demonstrated that the …

Gγ 13 is a divergent member of the Gγ subunit family considered to be a component of the
gustducin G-protein heterotrimer involved in bitter and sweet taste reception in taste bud …

The human T1R taste receptors are family CG‐protein‐coupled receptors (GPCRs) that act
as heterodimers to mediate sweet (hT1R2+ hT1R3) and umami (hT1R1+ hT1R3) taste …