Purpose To test the hypothesis—given the increasing emphasis on quantitative computed
tomographic (CT) phenotypes of chronic obstructive pulmonary disease (COPD)—that a …

COPD (chronic obstructive pulmonary disease) is a heterogeneous disease associated with
significant morbidity and mortality. Current diagnostic criteria based on the presence of fixed …

Chronic obstructive pulmonary disease (COPD) is a common, complex disease associated
with significant and increasing morbidity and mortality. The cardinal feature of COPD is …

Background Several criteria are clinically applied in the assessment of significant
bronchodilator responsiveness in chronic obstructive pulmonary disease (COPD). The …

Purpose Drug development in chronic obstructive pulmonary disease (COPD) has been
characterised by unacceptably high failure rates. In addition to the poor sensitivity in forced …

Introduction This study aimed to characterize patients with chronic obstructive pulmonary
disease (COPD) newly prescribed a long-acting bronchodilator (LABD), and to assess …

As the clinical and research focus of chronic obstructive pulmonary disease (COPD) evolves
from regarding obstructive lung disease as a single disease entity to recognizing the …

Chronic obstructive pulmonary disease (COPD) phenotyping can help define clusters of
patients with common characteristics that relate to clinically meaningful outcomes. In this …

Treatment of COPD should reflect the complexity and heterogeneity of the disease and be
tailored to individual patients. Major goals of COPD treatment are symptom reduction and …

Chronic obstructive pulmonary disease (COPD) is a complex disorder and not all patients
respond to all available drugs. The importance of personalized treatment in COPD is …