Background: In 2008, a dedicated American Thoracic Society/European Respiratory Society
task force published a paper on the possible use and limitations of clinical outcomes and …

The significant healthcare burden associated with chronic obstructive pulmonary disease
(COPD) is driving us to improve our understanding of the natural history of this disease …

The management of chronic obstructive pulmonary disease (COPD) has improved markedly
over recent years with the combination of more effective drug treatments, and …

Chronic obstructive pulmonary disease (COPD) is now considered a markedly complex and
heterogeneous disease [1]. In the latest update of the Global Initiative for Chronic …

The previous French Society of Respiratory Diseases (SPLF, Société de Pneumologie de
Langue Française) position paper on pharmacological treatment optimization in stable …

Introduction Clinical studies demonstrate an accelerated decline in lung function in patients
with moderate chronic obstructive pulmonary disease (COPD)(Global Initiative for Chronic …

Introduction According to the Global Initiative for chronic obstructive lung disease (GOLD),
when a treatment is not achieving an appropriate response it should be switched taking into …

Chronic obstructive pulmonary disease (COPD) is a complex genetic disease that develops
as a result of the interaction of multiple susceptibility genes and environmental factors. Major …

Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease and not well
understood. The forced expiratory volume in one second is used for the diagnosis and …

Background and objective Profiles of people with chronic obstructive pulmonary disease
(COPD) often do not describe treatable traits, lack validation and/or their stability over time is …