Oxidative balance is emerging as an important issue in understanding the pathogenesis of
Alzheimer's disease. Examination of Alzheimer's disease brain has demonstrated a great …

Alzheimer's disease (AD) is the most common cause of dementia and a progressive
neurodegeneration that appears to result from multiple pathogenic mechanisms (including …

Oxidative stress occurs early in the progression of Alzheimer disease, significantly before
the development of the pathologic hallmarks, neurofibrillary tangles and senile plaques. All …

Recent evidence in the field of Alzheimer disease research has highlighted the importance
of oxidative processes in its pathogenesis. Examination of cellular changes shows that …

Oxidative stress is a striking feature of susceptible neurons in the Alzheimer's disease brain.
Importantly, because oxidative stress is an early event in Alzheimer's disease, proximal to …

Research in Alzheimer disease has recently demonstrated compelling evidence on the
importance of oxidative processes in its pathogenesis. Cellular changes show that oxidative …

The risk of chronic diseases such as Alzheimer's disease is growing as a result of the
continuous increasing average life span of the world population, a syndrome characterized …

Oxidative stress is a marker of neurodegeneration and has been recently shown to be also
involved in the early stages of the pathogenesis of various neurodegenerative disorders. In …

The complex nature and genesis of oxidative damage in Alzheimer disease can be partly
answered by mitochondrial and redox-active metal abnormalities. By releasing high levels of …

The two most striking features of Alzheimer disease are (i) the multitude of abnormalities
affecting essentially every system and (ii) the strict age dependence. Recent work suggests …