Oxidative stress hypothesis in Alzheimer's disease
WR Markesbery - Free radical biology and medicine, 1997 - Elsevier
The major hurdle in understanding Alzheimer's disease (AD) is a lack of knowledge about
the etiology and pathogenesis of selective neuron death. In recent years, considerable data …
the etiology and pathogenesis of selective neuron death. In recent years, considerable data …
Oxidative stress signalling in Alzheimer's disease
Multiple lines of evidence demonstrate that oxidative stress is an early event in Alzheimer's
disease (AD), occurring prior to cytopathology, and therefore may play a key pathogenic role …
disease (AD), occurring prior to cytopathology, and therefore may play a key pathogenic role …
Causes of oxidative stress in Alzheimer disease
Oxidative stress is one of the earliest events of Alzheimer disease (AD), with implications as
an important mediator in the onset, progression and pathogenesis of the disease. The …
an important mediator in the onset, progression and pathogenesis of the disease. The …
Alzheimer's disease and oxidative stress: implications for novel therapeutic approaches
C Behl - Progress in neurobiology, 1999 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder with a deadly
outcome. AD is the leading cause of senile dementia and although the pathogenesis of this …
outcome. AD is the leading cause of senile dementia and although the pathogenesis of this …
Alzheimer s disease and oxidative stress: a review
M Pohanka - Current medicinal chemistry, 2014 - ingentaconnect.com
Alzheimer´ s disease (AD) is a neurodegenerative disorder with no known cure and rapid
rise in incidence. The predominant cognitive impairment is currently treated using cognitive …
rise in incidence. The predominant cognitive impairment is currently treated using cognitive …
Oxidative stress, synaptic dysfunction, and Alzheimer's disease
E Tönnies, E Trushina - Journal of Alzheimer's Disease, 2017 - content.iospress.com
Alzheimer's disease (AD) is a devastating neurodegenerative disorder without a cure. Most
AD cases are sporadic where age represents the greatest risk factor. Lack of understanding …
AD cases are sporadic where age represents the greatest risk factor. Lack of understanding …
Oxidant/antioxidant imbalance and the risk of Alzheimer's disease
AE Abdel Moneim - Current Alzheimer Research, 2015 - ingentaconnect.com
Alzheimer's disease (AD) is the most common form of dementia characterized by
progressive loss of memory and other cognitive functions among older people. Senile …
progressive loss of memory and other cognitive functions among older people. Senile …
Oxidative stress in Alzheimer's disease brain: new insights from redox proteomics
DA Butterfield, M Perluigi, R Sultana - European journal of pharmacology, 2006 - Elsevier
Alzheimer's disease, an age-related neurodegenerative disorder, is characterized clinically
by a progressive loss of memory and cognitive functions. Neuropathologically, Alzheimer's …
by a progressive loss of memory and cognitive functions. Neuropathologically, Alzheimer's …
Comparative biology and pathology of oxidative stress in Alzheimer and other neurodegenerative diseases: beyond damage and response
In this review, we consider comparative aspects of the biology and pathology of oxygen
radicals in neurodegenerative disease and how these findings have influenced our concept …
radicals in neurodegenerative disease and how these findings have influenced our concept …
Oxidative stress in Alzheimer's disease: why did antioxidant therapy fail?
T Persson, BO Popescu… - Oxidative medicine and …, 2014 - Wiley Online Library
Alzheimer's disease (AD) is the most common form of dementia in the elderly, with
increasing prevalence and no disease‐modifying treatment available yet. A remarkable …
increasing prevalence and no disease‐modifying treatment available yet. A remarkable …