Oxidative stress has been implicated in the pathogenesis of a number of diseases including
Alzheimer's disease (AD). The oxidative stress hypothesis of AD pathogenesis, in part, is …

Alzheimer's disease has a multifactorial pathogenesis. Among the various factors involved,
this review examines, in particular, the possibility of oxidative stress, meaning an imbalance …

Oxidative stress is known to play an important role in the pathogenesis of a number of
diseases. In particular, it is linked to the etiology of Alzheimer's disease (AD), an age-related …

Oxidative stress is induced by an imbalanced redox states, involving either excessive
generation of reactive oxygen species (ROS) or dysfunction of the antioxidant system. The …

Alzheimer's disease (AD) is the most common cause of disability in individuals aged> 65
years worldwide. AD is characterized by the abnormal deposition of amyloid β (Aβ) peptide …

Neurodegenerative disorders constitute a substantial proportion of neurological diseases
with significant public health importance. The pathophysiology of neurodegenerative …

Genetic and lifestyle-related risk factors for Alzheimer disease (AD) are associated with an
increase in oxidative stress, suggesting that oxidative stress is involved at an early stage of …

Redox impairment is a prominent feature of Alzheimer's disease (AD). It has led to the
“oxidative stress hypothesis”, which proposes antioxidants as beneficial therapeutic tools in …

Alzheimer's disease is the leading cause of dementia in the elderly and is defined by two
pathological hallmarks; the accumulation of aggregated amyloid beta and excessively …

Free radical formation, abnormalities in iron and copper distribution, and metal-catalyzed
oxidation have all been noted in Alzheimer disease and are thought to play an important …