Hippocampal atrophy is a marker of Alzheimer disease (AD). It remains unclear whether this
holds true for younger patients as well. Hippocampal volume was measured on MRI scans …

The hippocampal formation (HF) is known from pathological and MRI studies to be severely
atrophied in established Alzheimer's disease. However, it is unclear when the earliest …

Background: The cognitive continuum in the elderly population can be conceptually divided
into those who are functioning normally (control subjects), those with a mild cognitive …

Objectives: To determine the annual rates of volumetric change of the hippocampus and
temporal horn in cognitively normal elderly control subjects and individually matched …

Objective: To investigate the added value of hippocampal atrophy rates over whole brain
volume measurements on MRI in patients with Alzheimer disease (AD), patients with mild …

Aim This study investigated whether the characteristic changes in hippocampal atrophy
seen in coronal scans are useful for differentiating Alzheimer's disease (AD), amnestic mild …

The sensitivity of MRI volumetric measures to detect cognitive dysfunction is examined in 39
participants of an epidemiological field study (age 75–85, MMSE 19–30). According to …

Hippocampal formation (HF) atrophy, although common in normal aging, has unknown
clinical consequences. We used MRI to derive HF size measurements at baseline on 44 …

The progression of Alzheimer disease might be monitored by measuring the rate of
hippocampal volume loss by means of MRI. Research suggests that a reduction in …

We evaluated three groups of elderly individuals who were carefully screened to rule out
clinically significant diseases that could affect cognition. They were matched for age and …