Genetic variants and risk of lung cancer in never smokers: a genome-wide association study

Y Li, CC Sheu, Y Ye, M de Andrade, L Wang… - The lancet …, 2010 - thelancet.com
Background Lung cancer in individuals who have never smoked tobacco products is an
increasing medical and public-health issue. We aimed to unravel the genetic basis of lung …

Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women

Z Wang, WJ Seow, K Shiraishi… - Human molecular …, 2016 - academic.oup.com
Genome-wide association studies (GWAS) of lung cancer in Asian never-smoking women
have previously identified six susceptibility loci associated with lung cancer risk. To further …

Association of smoking and polygenic risk with the incidence of lung cancer: a prospective cohort study

P Zhang, PL Chen, ZH Li, A Zhang, XR Zhang… - British journal of …, 2022 - nature.com
Background Genetic variation increases the risk of lung cancer, but the extent to which
smoking amplifies this effect remains unknown. Therefore, we aimed to investigate the risk of …

Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia

Q Lan, CA Hsiung, K Matsuo, YC Hong, A Seow… - Nature …, 2012 - nature.com
To identify common genetic variants that contribute to lung cancer susceptibility, we
conducted a multistage genome-wide association study of lung cancer in Asian women who …

Molecular genetics of lung cancer in people who have never smoked

J Subramanian, R Govindan - The lancet oncology, 2008 - thelancet.com
Lung cancer is a major cause of cancer-related mortality in the USA, and tobacco smoke is
the major risk factor for this disease. However, many patients with lung cancer have never …

Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study

P Broderick, Y Wang, J Vijayakrishnan, A Matakidou… - Cancer research, 2009 - AACR
To explore the impact of common variation on the risk of developing lung cancer, we
conducted a two-phase genome-wide association (GWA) study. In phase 1, we compared …

Association analyses identify multiple new lung cancer susceptibility loci and their interactions with smoking in the Chinese population

J Dong, Z Hu, C Wu, H Guo, B Zhou, J Lv, D Lu… - Nature …, 2012 - nature.com
To find additional susceptibility loci for lung cancer, we tested promising associations from
our previous genome-wide association study (GWAS) of lung cancer in the Chinese …

Genetic polymorphisms and lung cancer risk: Evidence from meta-analyses and genome-wide association studies

C Liu, H Cui, D Gu, M Zhang, Y Fang, S Chen, M Tang… - Lung Cancer, 2017 - Elsevier
A growing number of studies investigating the association between Single Nucleotide
Polymorphisms (SNPs) and lung cancer risk have been published since over a decade ago …

[HTML][HTML] Increased risk of lung cancer in individuals with a family history of the disease: a pooled analysis from the International Lung Cancer Consortium

ML Coté, M Liu, S Bonassi, M Neri, AG Schwartz… - European journal of …, 2012 - Elsevier
BACKGROUND AND METHODS: Familial aggregation of lung cancer exists after
accounting for cigarette smoking. However, the extent to which family history affects risk by …

Genetic predisposition to lung cancer: comprehensive literature integration, meta-analysis, and multiple evidence assessment of candidate-gene association studies

J Wang, Q Liu, S Yuan, W Xie, Y Liu, Y Xiang, N Wu… - Scientific reports, 2017 - nature.com
More than 1000 candidate-gene association studies on genetic susceptibility to lung cancer
have been published over the last two decades but with few consensuses for the likely …