[HTML][HTML] SARS-CoV-2 variants show resistance to neutralization by many monoclonal and serum-derived polyclonal antibodies
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the global
COVID-19 pandemic infecting more than 106 million people and causing 2.3 million deaths …
COVID-19 pandemic infecting more than 106 million people and causing 2.3 million deaths …
Identification of broad, potent antibodies to functionally constrained regions of SARS-CoV-2 spike following a breakthrough infection
J Guenthoer, M Lilly, TN Starr… - Proceedings of the …, 2023 - National Acad Sciences
The antiviral benefit of antibodies can be compromised by viral escape especially for rapidly
evolving viruses. Therefore, durable, effective antibodies must be both broad and potent to …
evolving viruses. Therefore, durable, effective antibodies must be both broad and potent to …
Evidence of escape of SARS-CoV-2 variant B. 1.351 from natural and vaccine-induced sera
The race to produce vaccines against severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) began when the first sequence was published, and this forms the basis for …
(SARS-CoV-2) began when the first sequence was published, and this forms the basis for …
BNT162b2-elicited neutralization of B. 1.617 and other SARS-CoV-2 variants
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is continuing to evolve
around the world, generating new variants that are of concern on the basis of their potential …
around the world, generating new variants that are of concern on the basis of their potential …
Neutralization of SARS-CoV-2 variants of concern harboring Q677H
The sensitivity of SARS-CoV-2 variants of concern (VOCs) to neutralizing antibodies has
largely been studied in the context of key receptor binding domain (RBD) mutations …
largely been studied in the context of key receptor binding domain (RBD) mutations …
Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain
Potent neutralizing monoclonal antibodies are one of the few agents currently available to
treat COVID-19. SARS-CoV-2 variants of concern (VOCs) that carry multiple mutations in the …
treat COVID-19. SARS-CoV-2 variants of concern (VOCs) that carry multiple mutations in the …
A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy
Many SARS-CoV-2 variants have mutations at key sites targeted by antibodies. However, it
is unknown if antibodies elicited by infection with these variants target the same or different …
is unknown if antibodies elicited by infection with these variants target the same or different …
SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization
D Mannar, JW Saville, Z Sun, X Zhu, MM Marti… - Nature …, 2022 - nature.com
Mutations in the spike glycoproteins of SARS-CoV-2 variants of concern have independently
been shown to enhance aspects of spike protein fitness. Here, we describe an antibody …
been shown to enhance aspects of spike protein fitness. Here, we describe an antibody …
[HTML][HTML] Reduced neutralization of SARS-CoV-2 B. 1.617 by vaccine and convalescent serum
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has undergone
progressive change, with variants conferring advantage rapidly becoming dominant …
progressive change, with variants conferring advantage rapidly becoming dominant …
Comparative analysis of SARS‐CoV‐2 Omicron BA. 2.12. 1 and BA. 5.2 variants
The initial severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) Omicron
subvariants, BA. 1 and BA. 2, are being progressively displaced by BA. 5 in many countries …
subvariants, BA. 1 and BA. 2, are being progressively displaced by BA. 5 in many countries …