[HTML][HTML] SARS-CoV-2 variants show resistance to neutralization by many monoclonal and serum-derived polyclonal antibodies

M Diamond, R Chen, X Xie, J Case, X Zhang… - Research …, 2021 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the global
COVID-19 pandemic infecting more than 106 million people and causing 2.3 million deaths …

Identification of broad, potent antibodies to functionally constrained regions of SARS-CoV-2 spike following a breakthrough infection

J Guenthoer, M Lilly, TN Starr… - Proceedings of the …, 2023 - National Acad Sciences
The antiviral benefit of antibodies can be compromised by viral escape especially for rapidly
evolving viruses. Therefore, durable, effective antibodies must be both broad and potent to …

Evidence of escape of SARS-CoV-2 variant B. 1.351 from natural and vaccine-induced sera

D Zhou, W Dejnirattisai, P Supasa, C Liu, AJ Mentzer… - Cell, 2021 - cell.com
The race to produce vaccines against severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) began when the first sequence was published, and this forms the basis for …

BNT162b2-elicited neutralization of B. 1.617 and other SARS-CoV-2 variants

J Liu, Y Liu, H Xia, J Zou, SC Weaver, KA Swanson… - Nature, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is continuing to evolve
around the world, generating new variants that are of concern on the basis of their potential …

Neutralization of SARS-CoV-2 variants of concern harboring Q677H

C Zeng, JP Evans, JN Faraone, P Qu, YM Zheng, L Saif… - MBio, 2021 - Am Soc Microbiol
The sensitivity of SARS-CoV-2 variants of concern (VOCs) to neutralizing antibodies has
largely been studied in the context of key receptor binding domain (RBD) mutations …

Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain

AK Wheatley, P Pymm, R Esterbauer, MH Dietrich… - Cell Reports, 2021 - cell.com
Potent neutralizing monoclonal antibodies are one of the few agents currently available to
treat COVID-19. SARS-CoV-2 variants of concern (VOCs) that carry multiple mutations in the …

A SARS-CoV-2 variant elicits an antibody response with a shifted immunodominance hierarchy

AJ Greaney, TN Starr, RT Eguia, AN Loes… - PLoS …, 2022 - journals.plos.org
Many SARS-CoV-2 variants have mutations at key sites targeted by antibodies. However, it
is unknown if antibodies elicited by infection with these variants target the same or different …

SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization

D Mannar, JW Saville, Z Sun, X Zhu, MM Marti… - Nature …, 2022 - nature.com
Mutations in the spike glycoproteins of SARS-CoV-2 variants of concern have independently
been shown to enhance aspects of spike protein fitness. Here, we describe an antibody …

[HTML][HTML] Reduced neutralization of SARS-CoV-2 B. 1.617 by vaccine and convalescent serum

C Liu, HM Ginn, W Dejnirattisai, P Supasa, B Wang… - Cell, 2021 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has undergone
progressive change, with variants conferring advantage rapidly becoming dominant …

Comparative analysis of SARS‐CoV‐2 Omicron BA. 2.12. 1 and BA. 5.2 variants

CP Ong, ZW Ye, K Tang, R Liang, Y Xie… - Journal of Medical …, 2023 - Wiley Online Library
The initial severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) Omicron
subvariants, BA. 1 and BA. 2, are being progressively displaced by BA. 5 in many countries …