Evolution and neutralization escape of the SARS-CoV-2 BA. 2.86 subvariant
Abstract Omicron BA. 2.86 subvariant differs from Omicron BA. 2 as well as recently
circulating variants by over 30 mutations in the spike protein alone. Here we report on the …
circulating variants by over 30 mutations in the spike protein alone. Here we report on the …
[HTML][HTML] Evolving antibody evasion and receptor affinity of the Omicron BA. 2.75 sublineage of SARS-CoV-2
Summary SARS-CoV-2 Omicron BA. 2.75 has diversified into multiple subvariants with
additional spike mutations and several are expanding in prevalence, particularly CH. 1.1 …
additional spike mutations and several are expanding in prevalence, particularly CH. 1.1 …
[HTML][HTML] The E484K mutation in the SARS-CoV-2 spike protein reduces but does not abolish neutralizing activity of human convalescent and post-vaccination sera.
One year in the coronavirus disease 2019 (COVID-19) pandemic, the first vaccines are
being rolled out under emergency use authorizations. It is of great concern that newly …
being rolled out under emergency use authorizations. It is of great concern that newly …
The landscape of antibody binding affinity in SARS-CoV-2 Omicron BA. 1 evolution
The Omicron BA. 1 variant of SARS-CoV-2 escapes convalescent sera and monoclonal
antibodies that are effective against earlier strains of the virus. This immune evasion is …
antibodies that are effective against earlier strains of the virus. This immune evasion is …
[PDF][PDF] Why does the Omicron sub-variant spread faster than the original
E Callaway - Nature, 2022 - puntoporpunto.com
The variant, known as BA. 2, has spread rapidly in countries including Denmark, the
Philippines and South Africa in the past few weeks. It follows the initial spread of the BA. 1 …
Philippines and South Africa in the past few weeks. It follows the initial spread of the BA. 1 …
Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift
The recently emerged SARS-CoV-2 Omicron variant encodes 37 amino acid substitutions in
the spike protein, 15 of which are in the receptor-binding domain (RBD), thereby raising …
the spike protein, 15 of which are in the receptor-binding domain (RBD), thereby raising …
Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants
Neutralizing antibodies (nAbs) elicited against the receptor binding site (RBS) of the spike
protein of wild-type severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are …
protein of wild-type severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are …
B. 1.526 SARS-CoV-2 variants identified in New York City are neutralized by vaccine-elicited and therapeutic monoclonal antibodies
H Zhou, BM Dcosta, MI Samanovic, MJ Mulligan… - MBio, 2021 - Am Soc Microbiol
ABSTRACT DNA sequence analysis recently identified the novel SARS-CoV-2 variant B.
1.526 that is spreading at an alarming rate in the New York City area. Two versions of the …
1.526 that is spreading at an alarming rate in the New York City area. Two versions of the …
Analysis of a SARS-CoV-2-infected individual reveals development of potent neutralizing antibodies with limited somatic mutation
Antibody responses develop following SARS-CoV-2 infection, but little is known about their
epitope specificities, clonality, binding affinities, epitopes, and neutralizing activity. We …
epitope specificities, clonality, binding affinities, epitopes, and neutralizing activity. We …
Therapeutic efficacy of monoclonal antibodies and antivirals against SARS-CoV-2 Omicron BA. 1 in Syrian hamsters
R Uraki, M Kiso, M Imai, S Yamayoshi, M Ito… - Nature …, 2022 - nature.com
The spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the
major antigen stimulating the host's protective immune response. Here we assessed the …
major antigen stimulating the host's protective immune response. Here we assessed the …