Prolonged wakefulness alters cortical excitability, which is essential for proper brain function
and cognition. However, besides prior wakefulness, brain function and cognition are also …

Cortical excitability depends on sleep-wake regulation, is central to cognition, and has been
implicated in age-related cognitive decline. The dynamics of cortical excitability during …

Several neuropsychiatric and neurological disorders have recently been characterized as
dysfunctions arising from a 'final common pathway'of imbalanced excitation to inhibition …

Prolonged wakefulness is associated not only with obvious changes in the way we feel and
perform but also with well-known clinical effects, such as increased susceptibility to seizures …

Circadian and homeostatic sleep-wake regulatory processes interact in a fine tuned manner
to modulate human cognitive performance. Dampening of the circadian alertness signal and …

Human performance is modulated by circadian rhythmicity and homeostatic sleep pressure.
Whether and how this interaction is represented at the regional brain level has not been …

Circadian rhythms have natural relative variations among humans known as chronotype.
Chronotype or being a morning or evening person, has a specific physiological …

Neurobiology and Neuroprotective Benefits of Sleep : CONTINUUM: Lifelong Learning in
Neurology Account Register Activate Subscription Help Subscribe American Academy of …

Sleep inertia is the impaired cognitive performance immediately upon awakening, which
decays over tens of minutes. This phenomenon has relevance to people who need to make …

Sleep strongly affects synaptic strength, making it critical for cognition, especially learning
and memory formation. Whether and how sleep deprivation modulates human brain …