Molecular genetic methods have successfully been employed in research on rare,
monogenic diseases. Spurred by this success, researchers have employed the same …

Etiological heterogeneity and complexity has hampered attempts to identify predisposing
genes for schizophrenia. We sought to minimize the number of segregating genes involved …

Schizophrenia is a severe mental disorder affecting∼ 1% of the world's population. Here,
we report the results from a three-stage genomewide screen performed in a study sample …

Background A recent analysis of 25 historical candidate gene polymorphisms for
schizophrenia in the largest genome-wide association study conducted to date suggested …

BACKGROUND: Twin and adoption studies have consistently implicated genes in the
etiology of schizophrenia. Molecular genetic studies have found some consistent support for …

Although evidence exists to support a heritable component to schizophrenia, few details are
understood about the genetics of the disorder. Presently, molecular genetic techniques …

Methods This article draws on published reports in major international journals in the field of
schizophrenia and human genetics. Results We summarise the major findings from family …

Schizophrenia is a severe mental disorder characterized by positive and negative
symptoms, such as psychosis and anhedonia, as well as cognitive deficits. Schizophrenia …

Context Identifying susceptibility genes for schizophrenia may be complicated by phenotypic
heterogeneity, with some evidence suggesting that phenotypic heterogeneity reflects …

Identification of a gene or genes that contribute to the development of schizophrenia, a
complex psychiatric disorder, may be possible through genetic linkage analysis. Although to …